Encefalitis rábica humana secundaria a mordedura por gato infectado por un virus rábico de origen silvestre

Claro, Marlon Mauricio Bustos; Álvarez, Albert Alejandro Ávila; Carrascal, Elkin José Beltrán; Martínez, Leonar Giovanni Aguiar; Benigni, Eugenio Aladino Meek; Beltran, A.; Ayala, Juan Alejandro Méndez

doi:10.1016/s0123-9392(13)70725-2

Cited by 5 publications

(4 citation statements)

References 12 publications

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“…In spite of the aggressive therapeutic attempts, human rabies is still a fatal disease 4,14 . Survival in cases with some neurological sequels have been reported, probably related to early development of neutralizing antibodies against the virus, which happens in a small proportion of patients 15 .…”

Section: Discussionmentioning

confidence: 99%

“…Rabies is a zoonotic disease, with worldwide distribution, except for Antarctica; annual human cases are estimated to be around 75,000, with highest incidence rates reported in Asia and Africa 1,2 . In Colombia, rabies is in the list of notifiable diseases since 1970, and there is a specific strategic plan for the elimination of human rabies transmitted by dogs or bats, which has resulted in a significant reduction of human cases 3,4 .…”

Section: Introductionmentioning

confidence: 99%

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Rabies encephalitis and extra-neural manifestations in a patient bitten by a domestic cat

Soler-Rangel

Jiménez-Restrepo

Nariño

et al. 2020

Rev. Inst. Med. trop. S. Paulo

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Rabies encephalitis is a fatal zoonotic viral disease transmitted to humans either by domestic animals like dogs and cats or by wild animals like bats, skunks and raccoons. We present the case of a 25-year-old woman admitted due to behavioral disorders, generalized paresthesiasand acute respiratory deterioration compatible with a respiratory distress syndrome (ARDS) requiring orotracheal intubation, mechanical ventilation and empirical initiation of antibiotic and antiviral therapy. Chest tomography showed pneumomediastinum and changes suggestive of pulmonary infection. In the presence of neurological symptoms, a central nervous system (CNS) infection was suspected and the cerebrospinal fluid showed no pleocytosis, hiperproteinorrachy without glucose consumption; cranial CT scan was normal. During hospitalization, the family reported that the patient was bitten by a cat 30-day prior to the onset of rabies-like symptoms, and the animal was sacrificed. The patient had an unfavorable clinical evolution, with electroencephalographic activity dissociation evidenced by video telemetry. The zoonotic exposure led to the suspected diagnosis of rabies infection. The patient died and the suspected diagnosis was confirmed by histopathology, with presence of Negri bodies on cerebellum Purkinje cells and a positive immunofluorescence test for rabies virus. Both, initial extra-neural manifestations and late reporting of rabies exposure led to delayed diagnosis.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Rabies encephalitis and extra-neural manifestations in a patient bitten by a domestic cat

Soler-Rangel

Jiménez-Restrepo

Nariño

et al. 2020

Rev. Inst. Med. trop. S. Paulo

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“…of bat strain rabies from terrestrial animals to humans also appears to be very rare: only three articles, all from South America, definitively identified the transmission of bat strain rabies to four humans via cats (23)(24)(25). These bats were vampire bats (Desmodus rotundus), which feed on mammalian blood, increasing the probability of infection in terrestrial animals; bats in Ontario feed on insects.…”

Section: Medianmentioning

confidence: 99%

Human rabies postexposure prophylaxis and rabid terrestrial animals in Ontario, Canada: 2014–2016

Middleton

Friedman

Johnson

et al. 2019

CCDR

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Background: The number of rabid terrestrial animals in Ontario has decreased markedly since the 1970s and 1980s. However, the number of recommended rabies postexposure prophylaxis (RPEP) courses has not decreased proportionally. The decision to recommend RPEP for terrestrial animal exposures should be based on a risk assessment that considers the prevalence of rabies in these animals within a jurisdiction, among other factors. Objective: To explore trends in RPEP recommendations for exposures to terrestrial animals in Ontario in relation to the recency of terrestrial animal rabies cases by public health unit (PHU) jurisdiction. Methods: RPEP recommendation data for the 36 Ontario PHUs were obtained from the Ontario integrated Public Health Information System and animal rabies data by PHU were obtained from the Ministry of Natural Resources and Forestry. We calculated the annual RPEP recommendation rates for terrestrial animals by PHU for 2014 to 2016, and plotted the 2016 rates in relation to the year of the most recently identified rabid terrestrial animal in the PHU. Results: Between 2014 and 2016, the annual RPEP recommendation rates for terrestrial animal exposures by PHU ranged from 3.0 to 35.2 per 100,000 persons, with a median of 11.9 RPEP recommendations per 100,000 persons. In 2016, ten PHUs had not identified a rabid terrestrial animal in their jurisdiction for more than 15 years. Five of these PHUs had RPEP recommendation rates above the provincial median. Conclusion: Along with other factors, consideration of the occurrence of rabies in terrestrial animals in a jurisdiction can assist in the risk assessment of dogs, cats or ferrets that are not available for subsequent observation.

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“…De plus, une recherche documentaire n'a permis de révéler qu'un seul article décrivant la transmission de la rage attribuable aux chauves-souris parmi les animaux terrestres, soit chez la mouffette en Arizona (22). De plus, la transmission de la rage attribuable aux chauves-souris par des animaux terrestres aux humains semble très rare : seuls trois articles, tous d'Amérique du Sud, ont identifié de manière définitive la transmission de la rage attribuable aux chauves-souris à quatre humains par l'entremise de chats (23)(24)(25). Il s'agissait de chauves-souris vampires (Desmodus rotundus) qui se nourrissent de sang de mammifères, ce qui accroît la probabilité d'infection chez les animaux terrestres; les chauves-souris de l'Ontario se nourrissent d'insectes.…”

Section: Surveillanceunclassified

Traitement préventif antirabique humain post-exposition et animaux terrestres enragés en Ontario, au Canada : de 2014 à 2016

Middleton¹,

Friedman²,

Johnson³

et al. 2019

RMTC

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Contexte : Le nombre d'animaux terrestres enragés en Ontario affiche une forte baisse depuis les années 1970 et 1980. Cependant, le nombre de traitements préventifs antirabiques post-exposition (TPAPE) recommandés n'a pas diminué de manière proportionnelle. La décision de recommander un TPAPE lors d'une exposition à des animaux terrestres doit se fonder sur une évaluation du risque qui tient compte de la prévalence de la rage chez ces animaux au sein d'un territoire, entre autres facteurs. Objectif : Explorer les tendances en matière de recommandations de TPAPE vis-à-vis de l'exposition à des animaux terrestres en Ontario par rapport la date du dernier cas de rage chez les animaux terrestres par territoire des bureaux de santé publique (BSP). Méthodologie : On a obtenu les données concernant les recommandations de TPAPE de 36 BSP de l'Ontario du système d'information en santé publique intégré ontarien et les données de rage animale par BSP du ministère des Richesses naturelles et des Forêts. Nous avons calculé les taux annuels de recommandation de TPAPE pour les animaux terrestres par BSP pour 2014 à 2016, puis mis en plan les taux de 2016 par rapport à l'année de la plus récente identification d'animal terrestre enragé au sein du BSP. Résultats : Entre 2014 et 2016, les taux annuels de recommandation de TPAPE pour l'exposition à des animaux terrestres par BSP allaient de 3,0 à 35,2 par 100 000 personnes, avec une médiane de 11,9 recommandations de TPAPE par 100 000 personnes. En 2016, 10 BSP n'avaient pas identifié d'animal terrestre enragé dans leur compétence depuis plus de 15 ans. Cinq de ces BSP présentaient des taux de recommandation de TPAPE supérieurs à la médiane provinciale. Conclusion : Conjuguée à d'autres facteurs, la considération de la présence de rage chez des animaux terrestres dans un territoire peut simplifier l'évaluation du risque concernant les chiens, chats ou furets qui ne sont pas accessibles pour fin d'observation ultérieure.

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Encefalitis rábica humana secundaria a mordedura por gato infectado por un virus rábico de origen silvestre

Cited by 5 publications

References 12 publications

Rabies encephalitis and extra-neural manifestations in a patient bitten by a domestic cat

Rabies encephalitis and extra-neural manifestations in a patient bitten by a domestic cat

Human rabies postexposure prophylaxis and rabid terrestrial animals in Ontario, Canada: 2014–2016

Traitement préventif antirabique humain post-exposition et animaux terrestres enragés en Ontario, au Canada : de 2014 à 2016

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