Encapsulation of trans-resveratrol in poly(ε-caprolactone) by GAS antisolvent

Sakata, Guilherme S.B.; Ribas, Marcela M.; Magro, Camila Dal; Santos, Aline Elias dos; Aguiar, Gean Pablo S.; Oliveira, J. Vladimir; Lanza, Marcelo

doi:10.1016/j.supflu.2021.105164

Cited by 14 publications

(2 citation statements)

References 42 publications

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“…32 Moreover, the encapsulation of RSV using poly--caprolactone through antisolvent technique was successfully enhanced the thermal-oxidative properties by 2.51 times higher than that of unencapsulated RSV. 33 A similar study reported that RSV was also encapsulated and obtained particle size around 250 nm that improved potential activity on immunostimulant and enhanced lung bioavailability. 34 RSV encapsulated into the nano-polymeric system along with chitosan (CS) and γ-poly glutamic acid (γ-PGA) through an ion gelation technique increased the solubility of RSV 4.2fold.…”

Section: Polymeric Nanoparticlementioning

confidence: 93%

Antioxidant activity and nano delivery of the most frequently applied stilbene derivatives: A brief and recent review

Choiri¹,

Fitriastuti²,

Faradiva³

et al. 2021

Pharm Sci

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As of recent, the appearance rate of several degenerative diseases and cancer influenced by oxidative stress continues to increase dramatically. Many compounds with high potential antioxidant activity have been explored and used extensively, i.e., as preventive or curative treatments. Stilbene and its derivates have high potential antioxidant activity contained in several botanical sources. To date, source exploration and antioxidant activity study of stilbene derivate has been reported. However, the nano-delivery of stilbene derivate meant to increase the antioxidant activity and stability is still a limited process. This review is devoted to brief and recent outlooks regarding the antioxidant activity and delivery system of the most frequently applied stilbene and its derivates, namely resveratrol and pterostilbene.

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Section: Polymeric Nanoparticlementioning

confidence: 93%

Antioxidant activity and nano delivery of the most frequently applied stilbene derivatives: A brief and recent review

Choiri¹,

Fitriastuti²,

Faradiva³

et al. 2021

Pharm Sci

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show abstract

“…Encapsulation was positive because it did not change the chemical structures or the antioxidant activity of resveratrol. In addition, the microparticles maintained a constant release for 48 h and, in the thermal oxidative analysis, the difference between the samples and the control was 2.57 times smaller than the difference between pure resveratrol and the control sample [ 206 ]. Curcumin nanoparticles were also produced by encapsulation in Shellac by the GAS technique.…”

Section: Applications Of Encapsulated Productsmentioning

confidence: 99%

Encapsulation of Bioactive Compounds for Food and Agricultural Applications

et al. 2022

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This review presents an updated scenario of findings and evolutions of encapsulation of bioactive compounds for food and agricultural applications. Many polymers have been reported as encapsulated agents, such as sodium alginate, gum Arabic, chitosan, cellulose and carboxymethylcellulose, pectin, Shellac, xanthan gum, zein, pullulan, maltodextrin, whey protein, galactomannan, modified starch, polycaprolactone, and sodium caseinate. The main encapsulation methods investigated in the study include both physical and chemical ones, such as freeze-drying, spray-drying, extrusion, coacervation, complexation, and supercritical anti-solvent drying. Consequently, in the food area, bioactive peptides, vitamins, essential oils, caffeine, plant extracts, fatty acids, flavonoids, carotenoids, and terpenes are the main compounds encapsulated. In the agricultural area, essential oils, lipids, phytotoxins, medicines, vaccines, hemoglobin, and microbial metabolites are the main compounds encapsulated. Most scientific investigations have one or more objectives, such as to improve the stability of formulated systems, increase the release time, retain and protect active properties, reduce lipid oxidation, maintain organoleptic properties, and present bioactivities even in extreme thermal, radiation, and pH conditions. Considering the increasing worldwide interest for biomolecules in modern and sustainable agriculture, encapsulation can be efficient for the formulation of biofungicides, biopesticides, bioherbicides, and biofertilizers. With this review, it is inferred that the current scenario indicates evolutions in the production methods by increasing the scales and the techno-economic feasibilities. The Technology Readiness Level (TRL) for most of the encapsulation methods is going beyond TRL 6, in which the knowledge gathered allows for having a functional prototype or a representative model of the encapsulation technologies presented in this review.

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The technology for improving stability of nanosuspensions in drug delivery

Guan

Ding

et al. 2022

J Nanopart Res

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Encapsulation of trans-resveratrol in poly(ε-caprolactone) by GAS antisolvent

Cited by 14 publications

References 42 publications

Antioxidant activity and nano delivery of the most frequently applied stilbene derivatives: A brief and recent review

Antioxidant activity and nano delivery of the most frequently applied stilbene derivatives: A brief and recent review

Encapsulation of Bioactive Compounds for Food and Agricultural Applications

The technology for improving stability of nanosuspensions in drug delivery

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