Encapsulation of resveratrol in biopolymer particles produced using liquid antisolvent precipitation. Part 2: Stability and functionality

Joye, Iris J.; Davidov‐Pardo, Gabriel; McClements, David Julian

doi:10.1016/j.foodhyd.2015.02.038

Cited by 150 publications

(64 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The results obtained for the influence of ionic strength disagreed with the findings of Joye et al ( 2015 ), since there was no evidence of any effect of ionic strength on the synthesis of the particles. When the pH of the aqueous phase was increased from 2 to 7.4, the mean diameter and polydispersity index values decreased, while when the pH was further increased from 7.4 to 10, the diameter and polydispersity of the particles increased.…”

Section: Strategies To Improve the Stability Of Zein Nanoparticlescontrasting

confidence: 90%

“…The coated particles presented a larger average diameter, compared to particles not coated with the emulsifiers, together with improved performance in the chemical stability parameters evaluated during 30 days in the presence of ultraviolet light. Joye et al ( 2015 ) reported that the coating of zein nanoparticles with sodium caseinate was effective in improving the stability of nanoparticles loaded with resveratrol, considering the effects of ionic strength, pH, and temperature during storage for 4 weeks. In a study of synthesized zein nanoparticles loaded with resveratrol and coated with pectin, Huang et al ( 2017 ) reported an important influence of the pectin concentration on the stability of the formulation, although no data were provided for the chemical stability of the particles according to time, temperature, or pH.…”

Section: Strategies To Improve the Stability Of Zein Nanoparticlesmentioning

confidence: 99%

See 1 more Smart Citation

Zein Nanoparticles and Strategies to Improve Colloidal Stability: A Mini-Review

2018

View full text Add to dashboard Cite

Zein, a protein extracted from maize, can be employed to easily produce nanoscale particles suitable for use as carrier systems. This review investigates the main methods for obtaining zein nanoparticles, as well as the problems and options available in the development of stable colloidal suspensions. Considerable gaps were identified in the literature concerning this topic, with studies being unclear about the factors that affect the stability of zein particles. In the vast majority of cases, no data are presented in relation to the stability of the formulations over time. It could be concluded that in order to produce a high quality system, detailed evaluation is required, considering factors including the zein concentration, pH, ionic strength, thermal treatment of the protein prior to preparation of the nanoparticles, strategies employing other materials as coatings, and the storage conditions. It is extremely important that these aspects should be considered during product development, prior to commercial-scale manufacture.

show abstract

Section: Strategies To Improve the Stability Of Zein Nanoparticlescontrasting

confidence: 90%

Section: Strategies To Improve the Stability Of Zein Nanoparticlesmentioning

confidence: 99%

Zein Nanoparticles and Strategies to Improve Colloidal Stability: A Mini-Review

2018

View full text Add to dashboard Cite

show abstract

“…The antisolvent precipitation method has been used to form microgels to encapsulate a wide range of bioactive agents, including carotenoids [113], curcumin [114,115], quercetin [116]and resveratrol [117,118]…”

Section: Antisolvent Precipitationmentioning

confidence: 99%

Designing biopolymer microgels to encapsulate, protect and deliver bioactive components: Physicochemical aspects

McClements

2017

Advances in Colloid and Interface Science

Self Cite

211

125

View full text Add to dashboard Cite

Biopolymer microgels have considerable potential for their ability to encapsulate, protect, and release bioactive components. Biopolymer microgels are small particles (typically 100nm to 1000μm) whose interior consists of a three-dimensional network of cross-linked biopolymer molecules that traps a considerable amount of solvent. This type of particle is also sometimes referred to as a nanogel, hydrogel bead, biopolymer particles, or microsphere. Biopolymer microgels are typically prepared using a two-step process involving particle formation and particle gelation. This article reviews the major constituents and fabrication methods that can be used to prepare microgels, highlighting their advantages and disadvantages. It then provides an overview of the most important characteristics of microgel particles (such as size, shape, structure, composition, and electrical properties), and describes how these parameters can be manipulated to control the physicochemical properties and functional attributes of microgel suspensions (such as appearance, stability, rheology, and release profiles). Finally, recent examples of the utilization of biopolymer microgels to encapsulate, protect, or release bioactive agents, such as pharmaceuticals, nutraceuticals, enzymes, flavors, and probiotics is given.

show abstract

“…However, the utilisation of RES is hampered because of its poor water solubility and low stability, which limits its biological activity in vitro and in vivo (Walle, ). β‐cyclodextrin, hydroxypropyl‐β‐cyclodextrin, methylated‐β‐cyclodextrin, maltosyl‐β‐cyclodextrin, bile acids (Amri et al ., ), lipid (Neves et al ., ), poly (epsilon‐caprolactone) and poly (d, l‐lactic‐co‐glycolic acid)‐poly (ethylene glycol) blend (Sanna et al ., ), hydroxypropylmethyl cellulose (Zhang et al ., ), zein and gliadin (Davidov‐Pardo et al ., ; Joye et al ., ) have been reported for the improvement of RES solubility. These materials can usually encapsulate RES to form the microparticles (MPs) or nanoparticles, which can well improve the stability and water solubility.…”

Section: Introductionmentioning

confidence: 99%

“…Microencapsulation system can be fabricated using antisolvent precipitation method which has already been used to produce particles encapsulating different bioactive molecules (Gan et al, 2011;Li et al, 2012;Subia & Kundu, 2013;Davidov-Pardo et al, 2015;Joye et al, 2015). An antisolvent is added to a solvent in which the biopolymers are dissolved so as to induce supersaturation of the biopolymer, which provides the driving force for nucleation and subsequent particle growth (Joye & McClements, 2013).…”

Section: Introductionmentioning

confidence: 99%

Preparation and physicochemical characterisation of resveratrol–ovalbumin microparticles

Chen

et al. 2015

Int J of Food Sci Tech

View full text Add to dashboard Cite

Summary Resveratrol (RES) is a phenolic compound which has many biological activities, but its poor stability and water solubility limit its function and application. This study developed microparticles (MPs) using ovalbumin (OVA) as a matrix to encapsulate RES. Encapsulation efficiency, solubility and structural characteristics have been evaluated. The antioxidant activity of encapsulated RES has also been examined using the methods of the 2,2‐diphenyl‐1‐picrylhydrazyl (DPPH) and 2,2′‐azinobis(3‐ethylbenzothiazoline‐6‐sulphonic acid) (ABTS) radical scavenging assays. Moreover, the stability of the MPs in simulated gastric and intestinal fluid has been studied. In conclusion, RES can be effectively encapsulated by OVA to form spherical MPs resulting in its high water solubility. RES–OVA MPs may not only keep the antioxidant activity of RES but also promote its stability. This kind of MPs can have a potential application in the formulation of functional soft drink based on RES.

show abstract

Encapsulation of resveratrol in biopolymer particles produced using liquid antisolvent precipitation. Part 2: Stability and functionality

Cited by 150 publications

References 36 publications

Zein Nanoparticles and Strategies to Improve Colloidal Stability: A Mini-Review

Zein Nanoparticles and Strategies to Improve Colloidal Stability: A Mini-Review

Designing biopolymer microgels to encapsulate, protect and deliver bioactive components: Physicochemical aspects

Preparation and physicochemical characterisation of resveratrol–ovalbumin microparticles

Contact Info

Product

Resources

About