Encapsulation of Probiotic Bacillus coagulans for Enhanced Shelf Life

doi:10.7324/jabb.2017.50409

Cited by 3 publications

(2 citation statements)

References 41 publications

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“…In short, an effective microencapsulation system should protect them during GIT and storage, release them in the colon, and promote their colonization ability. Meanwhile, it is imperative to develop the right in vitro and in vivo models to evaluate the efficiency of these ADSs. − …”

Section: Applicationsmentioning

confidence: 99%

Microencapsulation for Pharmaceutical Applications: A Review

Yan,

Kim

2024

ACS Appl. Bio Mater.

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In order to improve bioavailability, stability, control release, and target delivery of active pharmaceutical ingredients (APIs), as well as to mask their bitter taste, to increase their efficacy, and to minimize their side effects, a variety of microencapsulation (including nanoencapsulation, particle size <100 nm) technologies have been widely used in the pharmaceutical industry. Commonly used microencapsulation technologies are emulsion, coacervation, extrusion, spray drying, freeze-drying, molecular inclusion, microbubbles and microsponge, fluidized bed coating, supercritical fluid encapsulation, electro spinning/spray, and polymerization. In this review, APIs are categorized by their molecular complexity: small APIs (compounds with low molecular weight, like Aspirin, Ibuprofen, and Cannabidiol), medium APIs (compounds with medium molecular weight like insulin, peptides, and nucleic acids), and living microorganisms (such as probiotics, bacteria, and bacteriophages). This article provides an overview of these microencapsulation technologies including their processes, matrix, and their recent applications in microencapsulation of APIs. Furthermore, the advantages and disadvantages of these common microencapsulation technologies in terms of improving the efficacy of APIs for pharmaceutical treatments are comprehensively analyzed. The objective is to summarize the most recent progresses on microencapsulation of APIs for enhancing their bioavailability, control release, target delivery, masking their bitter taste and stability, and thus increasing their efficacy and minimizing their side effects. At the end, future perspectives on microencapsulation for pharmaceutical applications are highlighted.

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Section: Applicationsmentioning

confidence: 99%

Microencapsulation for Pharmaceutical Applications: A Review

Yan,

Kim

2024

ACS Appl. Bio Mater.

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“…during spray drying as well as freeze drying. Nonetheless the material of the encapsulating matrix is the determinant in survivability during the processing procedures, skimmed milk conferring maximum protection and xanthan gum the least ( 72 ).…”

Section: Factors Affecting Probiotics Viability During Encapsulationmentioning

confidence: 99%

Natural sources and encapsulating materials for probiotics delivery systems: Recent applications and challenges in functional food development

et al. 2022

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Probiotics are known as the live microorganisms which upon adequate administration elicit a health beneficial response inside the host by decreasing the luminal pH, eliminating the pathogenic bacteria in the gut as well as producing short chain fatty acids (SCFA). With advancements in research; probiotics have been explored as potential ingredients in foods. However, their use and applications in food industry have been limited due to restrictions of maintaining the viability of probiotic cells and targeting the successful delivery to gut. Encapsulation techniques have significant influence on increasing the viability rates of probiotic cells with the successful delivery of cells to the target site. Moreover, encapsulating techniques also prevent the live cells from harsh physiological conditions of gut. This review discusses several encapsulating techniques as well as materials derived from natural sources and nutraceutical compounds. In addition to this, this paper also comprehensively discusses the factors affecting the probiotics viability and evaluation of successful release and survival of probiotics under simulated gastric, intestinal conditions as well as bile, acid tolerant conditions. Lastly applications and challenges of using encapsulated bacteria in food industry for the development of novel functional foods have also been discussed in detail too. Future studies must include investigating the use of encapsulated bacterial formulations in in-vivo models for effective health beneficial properties as well as exploring the mechanisms behind the successful release of these formulations in gut, hence helping us to understand the encapsulation of probiotic cells in a meticulous manner.

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Spray Drying Encapsulation of Probiotics for Functional Food Formulation-A Review

Sarkar¹

2020

NTNF

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Health consciousness coupled with enhanced health care cost has led consumer's inclination towards functional foods. Documented health benefits have projected probiotics as a new functional ingredient in the current era of self-care and complementary medicine. It has been established that the probiotic viability is necessary for the exhibition of health benefits but is lost during processing, storage and gastrointestinal transit. Probiotic viability can be retained with the adoption of spray drying encapsulation technique and better survival of the encapsulated probiotics than the free cells in the food matrix have been reported. Major challenges faced during the encapsulation of probiotic by spray drying are modulation of processing parameter, selection of probiotic strains and coating materials and stability during gastric transit. Proper selection of probiotic strains and cell wall materials, modulation of technological parameters of spray drying and storage conditions would yield spray dried encapsulated probiotics with greater viability. Spray dried encapsulated probiotics had higher viability than free cells and its supplementation may be a practical alternative for better retention of viability and functionality of probiotics during the formulation of functional foods.

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Encapsulation of Probiotic Bacillus coagulans for Enhanced Shelf Life

Cited by 3 publications

References 41 publications

Microencapsulation for Pharmaceutical Applications: A Review

Microencapsulation for Pharmaceutical Applications: A Review

Natural sources and encapsulating materials for probiotics delivery systems: Recent applications and challenges in functional food development

Spray Drying Encapsulation of Probiotics for Functional Food Formulation-A Review

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