Encapsulation of phycocyanin by electrospraying: A promising approach for the protection of sensitive compounds

Schmatz, Daiane Angelica; Mastrantonio, Duna Joanol da Silveira; Costa, Jorge Alberto Vieira; Morais, Michele Greque de

doi:10.1016/j.fbp.2019.07.008

Cited by 41 publications

(10 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The encapsulation of PBP improves its thermal protection and preserves its active properties. In this context, the electrospraying method showed high encapsulation efficiency of phycocyanin [159] , with especial emphasis on the food industry. In addition, other techniques have been applied in the last years for the microencapsulation of phycocyanin [160] , [161] , [162] , [163] , [164] in order to increase its stability.…”

Section: Biotechnological Perspectives Of Pbpsmentioning

confidence: 99%

Phycobiliproteins: Structural aspects, functional characteristics, and biotechnological perspectives

Dagnino‐Leone

Figueroa

Castañeda

et al. 2022

Computational and Structural Biotechnology Journal

View full text Add to dashboard Cite

Section: Biotechnological Perspectives Of Pbpsmentioning

confidence: 99%

Phycobiliproteins: Structural aspects, functional characteristics, and biotechnological perspectives

Dagnino‐Leone

Figueroa

Castañeda

et al. 2022

Computational and Structural Biotechnology Journal

View full text Add to dashboard Cite

“…Schmatz et al. (2020) found that at higher polymer concentrations (>5% polyvinyl alcohol), dripping of the electrospraying solution from the needle was minimized, likely due to the formation of a more stable Taylor cone resulting in uniform electrospraying and chain entanglement. This allowed more particles to reach the collector plate, which could explain the higher yield observed when using higher ES100 concentrations in the current study.…”

Section: Discussionmentioning

confidence: 99%

“…In the GRAF-ES100 electrospray solution, higher ES100 concentrations resulted in higher yields, EE, and LC, whereas higher GRAF concentrations resulted in an initial increase in EE and LC and lower yields of the nanoparticles. Schmatz et al (2020) found that at higher polymer concentrations (>5% polyvinyl alcohol), dripping of the electrospraying solution from the needle was minimized, likely due to the formation of a more stable Taylor cone resulting in uniform electrospraying and chain entanglement. This allowed more particles to reach the collector plate, which could explain the higher yield observed when using higher ES100 concentrations in the current study.…”

Section: Effect Of Es100 and Graf Concentrationmentioning

confidence: 99%

Effect of electrospraying conditions on the properties of aspalathin‐Eudragit S100 nanoparticles and assessment of orogastrointestinal stability and membrane permeability

et al. 2022

View full text Add to dashboard Cite

Aspalathin, a C-glucosyl dihydrochalcone, could have beneficial effects in the gut through the modulation of the microbiome. However, aspalathin is susceptible to oxidative degradation. The effect of electrospraying conditions on encapsulation of an aspalathin-rich fraction prepared from green rooibos (GRAF; 40% aspalathin, m/m) with Eudragit S100 (ES100), a pH-sensitive release polymer, was investigated to enhance the stability of aspalathin. Electrospraying conditions were varied according to a central composite design, using ES100 concentrations of 1-6% (m/m), GRAF concentrations of 5-25% (m/m, relative to polymer concentration), and voltages of 10-25 kV. The varying conditions produced nanoparticles ranging in yield (60.3-83.7%), encapsulation efficiency, (20.5-81.8%), loading capacity (1.0-14.9%), particle size (183-260 nm), and polydispersity index (0.35-0.74). The GRAF nanoparticles and nanoparticles prepared with pure aspalathin were evaluated for stability and release of aspalathin at fixed pH-time combinations (pH 6.8, 5 min; pH 2, 120 min; pH 4, 60 min; and pH 7, 120 min), simulating the pH and residence/transit time at various locations of the orogastrointestinal tract. Nanoencapsulation decreased aspalathin degradation at all pH-time combinations (1.9-2.7 times less degradation; p < 0.05), except for pH 7, 120 min (p ≥ 0.05), thus offering protection from the pH of the upper gastrointestinal tract. Additionally, the parallel artificial membrane permeability assay and the Caco-2 monolayer model indicated that the low membrane permeability of aspalathin after nanoencapsulation was maintained that would limit absorption, ideal for delivery in the gut. Thus, nanoencapsulated aspalathin holds potential for the regulation of gut microbiota.

show abstract

“…The particles’ properties were analysed and optimized to achieve the best coating material concentration or composition of two distinct types, with the highest entrapment efficiency, particle size consistency, and stability. Some authors also explored the stability of encapsulated phycocyanin, describing thermal stability improvement and resistance to the acidic environment when alginate and chitosan were used together as coating materials [ 184 ] and thermal resistance up to 216 °C with full preservation of its antioxidant activity when encapsulated with PVA [ 194 ]. Concerning the encapsulation of A. platensis extract, phenolic-rich, carotenoid-rich, aqueous-based, and a commercial powder extract were evaluated as the core of four different encapsulation systems.…”

Section: Microalgae Encapsulationmentioning

confidence: 99%

Microalgae Encapsulation Systems for Food, Pharmaceutical and Cosmetics Applications

2020

View full text Add to dashboard Cite

Microalgae are microorganisms with a singular biochemical composition, including several biologically active compounds with proven pharmacological activities, such as anticancer, antioxidant and anti-inflammatory activities, among others. These properties make microalgae an interesting natural resource to be used as a functional ingredient, as well as in the prevention and treatment of diseases, or cosmetic formulations. Nevertheless, natural bioactives often possess inherent chemical instability and/or poor solubility, which are usually associated with low bioavailability. As such, their industrial potential as a health-promoting substance might be severely compromised. In this context, encapsulation systems are considered as a promising and emerging strategy to overcome these shortcomings due to the presence of a surrounding protective layer. Diverse systems have already been reported in the literature for natural bioactives, where some of them have been successfully applied to microalgae compounds. Therefore, this review focuses on exploring encapsulation systems for microalgae biomass, their extracts, or purified bioactives for food, pharmaceutical, and cosmetic purposes. Moreover, this work also covers the most common encapsulation techniques and types of coating materials used, along with the main findings regarding the beneficial effects of these systems.

show abstract

Encapsulation of phycocyanin by electrospraying: A promising approach for the protection of sensitive compounds

Cited by 41 publications

References 38 publications

Phycobiliproteins: Structural aspects, functional characteristics, and biotechnological perspectives

Phycobiliproteins: Structural aspects, functional characteristics, and biotechnological perspectives

Effect of electrospraying conditions on the properties of aspalathin‐Eudragit S100 nanoparticles and assessment of orogastrointestinal stability and membrane permeability

Microalgae Encapsulation Systems for Food, Pharmaceutical and Cosmetics Applications

Contact Info

Product

Resources

About