Encapsulation of Droplets Using Cusp Formation behind a Drop Rising in a Non-Newtonian Fluid

Poryles, Raphaël; Zenit, Roberto

doi:10.3390/fluids3030054

Cited by 7 publications

(3 citation statements)

References 36 publications

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“…Several past studies have shown that rising bubbles and droplets exhibit shape deformation due to the viscoelasticity of the ambient medium. 68,69 Therefore, to quantify the strength of elasticity of the ambient media in our experiments, we determined the Deborah number De (= Uτ / a ), defined as the product of polymer relaxation time ( τ ) and the characteristic strain rate . Here U is the droplet speed and a is the droplet diameter.…”

Section: Resultsmentioning

confidence: 99%

Deforming active droplets in viscoelastic solutions

et al. 2023

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Section: Resultsmentioning

confidence: 99%

Deforming active droplets in viscoelastic solutions

et al. 2023

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“…Previous studies underscore a substantial influence of such normal stresses on flow fields containing suspended particles. In fact, the observed stress gradients possess the potential to significantly influence the trajectory of suspended particles or induce deformations in the shape of pliable particles navigating through such flow-fields [35][36][37][38][39]. While the Carreua-Yasuda model can reasonably predict the velocity profile and total shear stresses in steady shear flows, it completely neglects the generation of normal stresses.…”

Section: Flow-field In the Microchannel Conveying Single-phase Mc-pbs...mentioning

confidence: 99%

Elasticity of Carrier Fluid: A Key Factor Affecting Mechanical Phenotyping in Deformability Cytometry

Houston,

Pouraria

2024

Preprint

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Recently, microfluidics deformability cytometry has emerged as a powerful tool for high throughput mechanical phenotyping of large populations of cells. These methods characterize cells by their mechanical fingerprints through exerting hydrodynamic forces and monitoring the resulting deformation. These devices have shown great promise for label free cytometry, yet there is a critical need to improve their accuracy and reconcile any discrepancies with other methods, such as atomic force microscopy. In this study, we employ computational fluid dynamics simulations and uncover how the elasticity of frequently used carrier fluids such as methyl-cellulose dissolved in phosphate-buffered saline is significantly influential to the resulting cellular deformation. We conducted CFD simulations that are conventionally used within the deformability cytometry field, which neglect fluid elasticity. Subsequently, we incorporated a more comprehensive model that simulates the viscoelastic nature of the carrier fluid. A comparison of the predicted stresses between these two approaches underscores the significance of the emerging elastic stresses in addition to the well-recognized viscous stresses along the channel. Furthermore, we utilize a two-phase flow model to predict the deformation of a promyelocyte (i.e. HL-60 cell type) within a hydrodynamic constriction channel. The obtained results highlight a substantial impact of the elasticity of carrier fluid on cellular deformation and raise questions about the accuracy of mechanical property estimates derived by neglecting elastic stresses.

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“…It is not clear about the reason for the appearance of negative wake, which is related to the non-Newtonian characteristics of the droplet such as the appearance of a pointed tail and the discontinuity of the rise velocity [56]. Capobianchi et al [56] argued that the concentration of viscoelastic stresses at the rear of the droplet is the main reason for the appearance and development of the sharp tail in the presence of high fluid viscoelasticity, while Poryles [58] experimentally demonstrated that the strong non-Newtonian behavior of the fluid is the main factor determining the length and width of the tail. When a Newtonian droplet moves upward in a non-Newtonian fluid with viscoelastic and shear-thinning properties, the shape of the droplet is closely linked to its volume and the non-Newtonian properties of the continuous-phase fluid.…”

Section: Viscoelastic Non-newtonian Fluidsmentioning

confidence: 99%

Droplet Shape and Drag Coefficients in Non‐Newtonian Fluids: A Review

Sun

2023

ChemBioEng Reviews

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The motion of droplets in non‐Newtonian fluids is widely present in ubiquitous industrial processes. Understanding the droplet motion characteristics is important for optimizing the design of related processes. Here the progress in the research on the droplet motion characteristics in non‐Newtonian fluids is reviewed. The mechanism of droplet deformation in non‐Newtonian fluids were elucidated, the influence of different rheological properties on droplet shape was discussed, and the empirical correlations of droplet aspect ratio were summarized. Moreover, the dimensionless correlations of drag coefficient were discussed. There are relatively few drag coefficient correlations of droplets in non‐Newtonian fluids, while the correlation of drag coefficients of bubbles in non‐Newtonian fluids can provide some reference. Finally, the possible prospects for future studies of the subject were proposed.

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Encapsulation of Droplets Using Cusp Formation behind a Drop Rising in a Non-Newtonian Fluid

Cited by 7 publications

References 36 publications

Deforming active droplets in viscoelastic solutions

Deforming active droplets in viscoelastic solutions

Elasticity of Carrier Fluid: A Key Factor Affecting Mechanical Phenotyping in Deformability Cytometry

Droplet Shape and Drag Coefficients in Non‐Newtonian Fluids: A Review

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