Encapsulation of cinnamon oil in whey protein counteracts the disturbances in biochemical parameters, gene expression, and histological picture of the liver and pancreas of diabetic rats

Nanoencapsulation of thyme essential oil: a new avenue to enhance its protective role against oxidative stress and cytotoxicity of zinc oxide nanoparticles in rats

“…These authors and others reported that the particle size and morphology of the produced ZnO-NPs were affected by pH variations, the concentration of zinc, the temperature, and the reaction time (Bala et al 2015 ). Additionally, MD, GA, and WPI were successfully used in the encapsulation of the oil in a ratio of 2:1 (polymer:oil) and the encapsulated oil showed similar characteristics to those reported using different polymers such as chitosan to protect the oil from oxidation and to improve its characteristics (Mohammed et al 2020 )…”

“…These authors and others reported that the particle size and morphology of the produced ZnO-NPs were affected by pH variations, the concentration of zinc, the temperature, and the reaction time (Bala et al 2015). Additionally, MD, GA, and WPI were successfully used in the encapsulation of the oil in a ratio of 2:1 (polymer:oil) and the encapsulated oil showed similar characteristics to those reported using different polymers such as chitosan to protect the oil from oxidation and to improve its characteristics (Mohammed et al 2020) In the current study, we defined various effects of ZnO-NPs in rats. The majority of these effects were the significant changes in body weight and the indices of blood chemistry, the alteration in antioxidant enzyme activity, the cytokines, cytogenetic, and the histological structure of the liver and kidney.…”

“…In the current study, WPI, MD, and GA were used in the encapsulation of the essential oil as a wall material; hence, we can propose another mechanism for ETO-induced protection. WPI is a well-known antioxidant and hepatoprotective agent (Gad et al 2011 ) due to its ability to increase the level of tissue glutathione (Bayrama et al 2009 ; Mohammed et al 2020 ). It is rich in the amino acids cysteine, α-lactoglobulin, bovine serum albumin, and β-lactoglobulin (Rodzik et al 2020 ).…”

Nanoencapsulation of thyme essential oil: a new avenue to enhance its protective role against oxidative stress and cytotoxicity of zinc oxide nanoparticles in rats

“…Additionally, MD, GA, and WPI were successfully used in the encapsulation of the oil in a ratio of 2: 1 (polymer: oil) and the encapsulated oil showed a rounded shape with an average diameter of 311.8 ± 27 nm and zeta potential of -21.63 mV. The encapsulation of thyme oil was carried out using different polymers such as chitosan to protect the oil from oxidation and to improve its characteristics (Mohammed et al, 2020) In the current study, we de ned various effects of ZnO-NPs in rats. The majority of these effects were the signi cant changes in body weight and the indices of blood chemistry, the alteration in antioxidant enzyme activity, the cytokines, cytogenetic, and the histological structure of liver and kidney.…”

“…In the current study, WPI, MD, and GA were used in the encapsulation of the essential oil as a wall material; hence, we can propose another mechanism for ETO-induced protection. WPI is a well-known antioxidant and hepatoprotective agent (Gad et al 2011) due to its ability to increase the level of tissue glutathione (Bayrama et al 2009;Mohammed et al, 2020). It is rich in the amino acids cysteine, αlactoglobulin, bovine serum albumin, and β-lactoglobulin (Morr and Ha 1993).…”