Encapsulation of bioactive agent (Curcumin, Moringa) in electrospun nanofibers – Some insights into recent research trends

Abstract

As the epidemic of coronavirus disease (COVID-19) has spread rapidly, health organizations around the world has made wearing face mask obligatory to prevent the spread of the infections for the wellness of the society. As wearing face masks become a daily routine, the usage of cloth facemasks from textile fabric, is popular among the public. Since antiquity, textiles have been proven to be intertwined with human lives and the integrant of these crucial materials are fibers. Particularly, nanofiber fabrics manufactured by electrospinning have attracted attention, owing to the better filtration efficiency and breathability. In addition, the electrospinning process provide opportunities to fine tuning of the surface functionality through polymer chemistry and an encapsulation of bioactive agents in single step process. This review opens up a new horizon in possible textile applications especially, an active layer of bioactive agent (Curcumin and Moringa) loaded nanofibrous fabrics-based facemasks for day to day life.

Hybrid Systems of Nanofibers and Polymeric Nanoparticles for Biological Application and Delivery Systems

“…Poly (caprolactone) (PCL) is another synthetic polymer, and was used in the work of Sundhari et al, where created PCL nanofibers proved to be a good scaffold for the promotion of cell differentiation. The structure of these nanofibers presented a smooth and uniform diameter, and with certain wettability of the nanofibers, there is potential to facilitate neurite outgrowth, promoting cell viability by including lignin nanoparticles in the PCL nanofibers [ 99 ].…”

Recent progress of filtration mechanism to fabricate the effective COVID-masks: A review

“…Compounds of bioactive causatives are discovered in plants, whole grains, and some foods like nuts, fruits, oils, and vegetables. Indoles, lignin's, lycopene resveratrol and, tannins are examples that exist in bioactive compounds and are being examined by researchers to help treat coronary artery disease, cancers, and other illnesses [115].…”

“…Engineering the surface area and porosity to an optimal status through the electrospinning method presents a large possibility of a face mask with a bioactive agent. The electrospinning process with changes in technology suchlike force spinning and emulsion or coaxial provide a low-cost process with possible morphological adjustment of the nanofiber surface and mass production capacity [115]. By optimizing the nanofibers collection time, polymer / bioactive causative concentration, and, nozzle position perform a significant function in estimating the surface of the resulting nanofibers in the role of an operative layer of the face mask fabric.…”

Virgin Coconut Oil as a New Concept for Periodontal Tissue Regeneration via Expressions of TNF-α and TGF-β1

“…Transforming growth factors (TGFs) are divided into TGF- α and TGF- β , which are synthesized by various normal cells and platelets. They affect the activation of macrophages, fibroblast proliferation, synthesis of connective tissue fibers and their matrix, local angiogenesis, healing, and also, regulation of lymphocytes [ 22 – 24 ]. TGF- β 1 is synthesized by various normal cells and platelets and affects macrophage activation, fibroblast proliferation, synthesis of connective tissue fibers and their matrix, local angiogenesis, healing, and regulation of T lymphocytes [ 25 , 26 ].…”