Enantioseparation of β-methyl-substituted amino acids with cyclodextrins by capillary zone electrophoresis☆

Ilisz, István; Fodor, Gyula; Iványi, Róbert; Szente, Lajos; Tóth, Géza; Péter, Antal

doi:10.1016/j.jchromb.2008.05.020

Cited by 12 publications

(4 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…When the ionic CDs interacts with a racemic mixture, analytes transfer from the surrounding water phase due to the electrophoretic migration of the charged CDs [87]. For CDEKC anionic [80] and cationic CDs [81] are produced, however, the dominant CDs group, due to its resolution powers and their commercial availability, are highly sulfated CDs (HS-CDs) [82]. Various types of CDs are highly effective for separation of racemic amino acids and their derivatives using the CDEKC [83,84].…”

Section: Mips Template In Capillary Electrophoresismentioning

confidence: 99%

Application of molecularly imprinted polymers in analytical chiral separations and analysis

Rutkowska

Płotka‐Wasylka

Morrison

et al. 2018

TrAC Trends in Analytical Chemistry

159

View full text Add to dashboard Cite

Over the last two decades the process of development and application of a new types of molecular imprinted polymer (MIP) sorbents in the field of analytical chemistry have been widely described in the literature. One of the new trends in analytical chemistry practice is the use of new types of MIP sorbents as specific sorption materials constituting the stationary phase in advanced separation techniques. The following review paper contains comprehensive information about the application of a specific and well defined MIP sorbents (with the data base in the paper about the reagents used in MIP preparation process) as stationary phases in separation techniques including high performance liquid chromatography and capillary electrochromatography. Coverage includes newly created types of stationary phases (MIP sorbents) used for chiral recognition, with the focus on applications in enantioselective separation.

show abstract

Section: Mips Template In Capillary Electrophoresismentioning

confidence: 99%

Application of molecularly imprinted polymers in analytical chiral separations and analysis

Rutkowska

Płotka‐Wasylka

Morrison

et al. 2018

TrAC Trends in Analytical Chemistry

159

View full text Add to dashboard Cite

show abstract

“…When the charged CDs interact with racemic amino acids, the analytes migrate at a different velocity from a surrounding aqueous phase due to the electrophoretic migration of the ionic CDs. Although various anionic [34][35][36][37][38][39][40][41][42][43] and cationic CDs [44][45][46][47][48][49][50][51][52][53][54][55][56][57][58][59][60][61][62] are synthesized for CDEKC as summarized in Table 2, sulfated CDs (S-CDs) [34,35] and highly sulfated CDs (HS-CDs) [36][37][38][39][40][41] are still the predominant CSs due to their resolution powers and commercial-availability. Since commercially available S-CDs and HS-CDs from Beckmann Coulter are not single isomers but a mixture of sulfated CDs with a different degree of substitution (average; 9 and 12, respectively), a wide range of OTG, 1-S-octyl-␤-d-thioglucopyranoside; DTDP, 3-(4,6-dichloro-1,3,5-triazinylamino)-7-dimethyamino-2-methylphenazine; LED-IF, light-emitting diode-induced fluorescence.…”

Section: Cdekcmentioning

confidence: 99%

Recent progress in capillary electrophoretic analysis of amino acid enantiomers

Kitagawa

Otsuka

2011

Journal of Chromatography B

103

View full text Add to dashboard Cite

“…A further increase in concentration could result in either a slow or a rapid decrease in resolution. In addition, considering that the migration times continuously increased with increasing the CD concentration [25], a 10 mM concentration of HP-c-CD was chosen for further optimization of the separation.…”

Section: Effect Of the CD Concentrationmentioning

confidence: 99%

Enantioseparation of the New Antifungal Drug Iodiconazole and Structurally Related Triadimenol Analogues by CE with Neutral Cyclodextrin Additives

Zhao

Tan

et al. 2011

Chromatographia

View full text Add to dashboard Cite

Chiral separation of iodiconazole, a new antifungal drug, and 12 new structurally related triadimenol analogues were studied by capillary electrophoresis with seven neutral cyclodextrins. It was found that hydroxypropyl-c-cyclodextrin (HP-c-CD) was the most effective chiral selector. Furthermore, the influence of the concentration of HP-c-CD, buffer pH, buffer concentration, temperature, and applied voltage was investigated, and the method was validated. The study of the analyte structure-enantioseparation relationships showed that substitutions in the side chains had important influences on enantiomeric separation.

show abstract

Enantioseparation of β-methyl-substituted amino acids with cyclodextrins by capillary zone electrophoresis☆

Cited by 12 publications

References 30 publications

Application of molecularly imprinted polymers in analytical chiral separations and analysis

Application of molecularly imprinted polymers in analytical chiral separations and analysis

Recent progress in capillary electrophoretic analysis of amino acid enantiomers

Enantioseparation of the New Antifungal Drug Iodiconazole and Structurally Related Triadimenol Analogues by CE with Neutral Cyclodextrin Additives

Contact Info

Product

Resources

About