Enantioseparation of Malathion, Cruformate, and Fensulfothion Organophosphorus Pesticides by Mixed-Mode Electrokinetic Capillary Chromatography

Chirality of organophosphorus pesticides: Analysis and toxicity

“…most research efforts focused on understanding the environmental fate and effects of legacy chiral pesticides [6,7,9,10]. Results from such studies have shown that enantiomers of the same chiral compound can degrade at significantly different rates [6,[11][12][13][14][15][16][17][18][19] and have very different toxicological characteristics in the environment [6,18,[20][21][22][23][24][25].…”

Enantiomeric separation of organophosphorus pesticides by high-performance liquid chromatography, gas chromatography and capillary electrophoresis and their applications to environmental fate and toxicity assays

“…This method was confirmed to be suitable for the determination of malathion (34) enantiomers in water samples spiked at g/mL levels, and it played an important role in validating analyses of trace chiral OPs. Anigbogu et al reported a chiral separation process for OPs using mixed-mode electrokinetic capillary chromatography (mixed-mode ECC), i.e., a combination of MECC and dual-cyclodextrin electrokinetic capillary chromatography (dual-CECC) [54]. It was demostrated that the versatility of the mixed-mode ECC in handing separation of OP enantiomers was achieved by combining three or more pseudostationary phases in the background electrolyte (BGE).…”

Simultaneous enantioselective determination of fenamiphos and its two metabolites in soil sample by CE

“…The micellar electrokinetic chromatography allowed the enantioseparation of neutral pesticides in the presence of negatively charged micelles and CD [13][14][15]. Nevertheless, this CE mode failed to resolve fenamiphos enantiomers [14]. The second approach has involved the complexing properties of charged CD to resolve mixtures of neutral enantiomeric pesticides.…”