Enantioselective toxic effects and digestion of furalaxyl enantiomers in Scenedesmus obliquus

Abstract

Research on the enantioselective environmental behavior of chiral pesticides has been a hot spot of environmental chemistry recently. In this study, the acute toxicity and digestion of furalaxyl enantiomers were determined on the aquatic algae Scendesmus obliquus. After exposure for 96 hours, the EC50 values for (S)‐furalaxyl and (R)‐furalaxyl were 13.59 and 15.26 mg/L, respectively. In addition, enantioselectivity was observed from the determined chlorophyll contents and antioxidant enzyme (CAT and SOD) activities of algae cells after exposure to furalaxyl enantiomers for 96 hours. The digestion rate of (S)‐furalaxyl and (R)‐furalaxyl were almost the same in S. obliquus. On the basis of these data, the inactive enantiomers (S)‐ furalaxyl is more toxic than the active one on the non‐target species S. obliquus, indicating that such enantiomeric differences should be taken into consideration in the study of pesticide risk assessment.

Oxidative Stress and Enantioselective Degradation of Dufulin on Tubifex

“…The first line of defense that stimulates the body to remove ROS is SOD. It can catalyze the transformation of superoxide anion (O 2− ) into H 2 O 2 and minimize oxidative damage to organisms (Xie et al 2011; Cheng et al 2018). The SOD activities were significantly induced in dufulin enantiomers and rac ‐dufulin treatments (Figure 2B).…”