Enantioselective behavior analysis of chiral fungicide tetraconazole in apples with UPLC-MS/MS

Li, Ye; Nie, Jun; Chang, Weixia; Xu, Guofeng; Farooq, Saqib; Li, Mingyu; Zhang, Jia

doi:10.1016/j.foodcont.2020.107305

Cited by 15 publications

(4 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[30] monitored the enantioselective dissipation of pydiflumetofen in grape and found (+)‐pydiflumetofen was preferentially enrichment. Enzyme system of plant is considered to be an important factor for enantioselective metabolism of chiral compounds [41]. In this study, the different enrichment of (+)‐oxathiapiprolin and (−)‐oxathiapiprolin in grape may be due to the molecular recognition or the bio‐affinity between enantiomers and specific enzyme in grapes.…”

Section: Resultsmentioning

confidence: 95%

Enantioseparation and dissipation monitoring of oxathiapiprolin in grape using supercritical fluid chromatography tandem mass spectrometry

Liu

Dong

et al. 2020

J of Separation Science

View full text Add to dashboard Cite

Oxathiapiprolin is a chiral fungicide used in China for the prevention and treatment of grape downy mildew, but its potential risk could be inaccurately assessed without distinguishing its enantiomers. In this study, an effective and sensitive chiral analytical method was first established for quantification of oxathiapiprolin enantiomers using supercritical fluid chromatography tandem mass spectrometry. Baseline separation for oxathiapiprolin enantiomers was achieved for less than 3 min by using a Lux Cellulose‐2 chiral column with the resolution of 1.51. The elution order of the eluting enantiomers was identified as (−)‐oxathiapiprolin and (+)‐oxathiapiprolin by an optical rotation detector. The grape samples were extracted by QuEChERS method, with the average recoveries of each enantiomer in grapes were in the range of 88.1–111.8% and the relative standard deviations were less than 18.9%. The enantioselective analysis of the dissipation of oxathiapiprolin in field grape samples showed that (−)‐oxathiapiprolin was dissipated faster than (+)‐oxathiapiprolin. The results indicate that this proposed method could provide data support for the risk assessment of oxathiapiprolin in agricultural produces in a more accurate way.

show abstract

Section: Resultsmentioning

confidence: 95%

Enantioseparation and dissipation monitoring of oxathiapiprolin in grape using supercritical fluid chromatography tandem mass spectrometry

Liu

Dong

et al. 2020

J of Separation Science

View full text Add to dashboard Cite

show abstract

“…The matrix effect (ME) was calculated by dividing the slope of the matrix standard curve by the slope of the solvent standard curve (slope ratio). ME > 1.1 indicates a matrix enhancement effect, ME < 0.9 indicates a matrix weakening effect, and 0.9 < ME < 1 indicates a negligible matrix effect (Li et al 2020). The accuracy and precision of the BH detection method were evaluated using additive recovery and relative standard deviation (RSD) (Ashour &Kattan 2013).…”

Section: Methods Validationmentioning

confidence: 99%

Migration behavior of benzobicyclon hydrolysate and associated influencing factors in different agricultural soils

Rao

Zhou

Tang

et al. 2021

Preprint

View full text Add to dashboard Cite

Abstract. Benzobicyclon is a triketone pro-herbicide that needs to be hydrolyzed to form an active compound benzobicyclon hydrolysate (BH). This study aimed to investigate the migration behavior of BH in different types of agricultural soil and the associated influencing factors. Soil thin-layer chromatography and column leaching tests were used to study the migration behavior of BH in these soils. Based on the mobility retention factor (Rf = 0.34–0.90), the mobility of BH in thin soil layers was ranked in the order Lixisols > Anthrosols > Ferralsols > Phaeozems. The Rf value of BH was linearly positively correlated with soil sand content and pH, and negatively correlated with other physical and chemical properties of soil. BH was difficult to leach in Phaeozems, less difficult to leach in Ferralsols, and easy to leach in Anthrosols and Lixisols. Increasing the BH dosage and rainfall amount or adding humic acid and anionic (dodecyl benzene sulfonic acid) or nonionic (Tween-80) surfactant blocked BH migration in soil columns. In contrast, increasing the leaching solution pH and adding cationic surfactant (cetyl trimethyl ammonium bromide) promoted BH migration in soil columns.BH application has a low risk of groundwater pollution in Phaeozems and Ferralsols, but poses a potential threat to groundwater in Anthrosols and Lixisols.

show abstract

Section: Introductionmentioning

confidence: 99%

“…To ensure the high quality and yield of vegetables, fruits, and crops around the world, pesticides are widely used in agricultural production to control pathogenic bacteria, pests, and weeds. , Triazole fungicides have the advantages of high efficiency, broad spectrum, low toxicity to nontarget organisms, and low resistance. Triazole fungicides can be used to control fungal diseases, such as powdery mildews, rusts, and many leaf spot fungi on a variety of plants. , In recent years, they have been widely used in the food and environmental fields. , Due to their moderate lipophilicity, long-term stability, and photochemical half-life, there is a problem of accumulation in waters such as rivers, wastewater, and lakes .…”

Section: Introductionmentioning

confidence: 99%

Enantioselective Dissipation, Residue, and Risk Assessment of Diniconazole Enantiomers in Four Kinds of Fruits

Teng

Wang

et al. 2021

J. Agric. Food Chem.

View full text Add to dashboard Cite

Chiral diniconazole is a widely used triazole fungicide, while its enantioselective behaviors in fruits have not been reported. In this article, the absolute configuration was confirmed. A fast supercritical fluid chromatography-tandem mass spectrometry (SFC-MS/MS) method was developed for the chiral separation and enantioselective study of diniconazole in four kinds of fruits. The residual concentrations gradually decreased with time in four kinds of fruits after applying diniconazole. The dissipation half-lives of R-diniconazole and S-diniconazole were in the range of 5.3–7.9 and 2.5–7.1 days respectively, and S-diniconazole was degraded preferentially. The residue concentrations were lower than the EU’s MRL (0.01 mg/kg) on the 40th (harvest time), 30th, and 10th day in pear, jujube, and apple, respectively. But, in peach, residue concentrations were still higher than the MRL after 60 days and the ratio of R/S was 2.2. These results could be helpful for the reasonable use and risk assessment of chiral diniconazole.

show abstract

Enantioselective behavior analysis of chiral fungicide tetraconazole in apples with UPLC-MS/MS

Cited by 15 publications

References 28 publications

Enantioseparation and dissipation monitoring of oxathiapiprolin in grape using supercritical fluid chromatography tandem mass spectrometry

Enantioseparation and dissipation monitoring of oxathiapiprolin in grape using supercritical fluid chromatography tandem mass spectrometry

Migration behavior of benzobicyclon hydrolysate and associated influencing factors in different agricultural soils

Enantioselective Dissipation, Residue, and Risk Assessment of Diniconazole Enantiomers in Four Kinds of Fruits

Contact Info

Product

Resources

About