Enantioselective assembly and recognition of heterochiral porous organic cages deduced from binary chiral components

Abstract

Heterochiral organic cages based on enantioselective self-assembly of binary chiral components have been prepared, exhibiting circularly polarized luminescence property and enantioselective recognition ability towards chiral substrates according to the circular dichroism spectral change.

Cage-based sensors for circular dichroism analysis

“…Jiang and coworkers synthesized the heterochiral cage C10 with two chiral components through imide condensation (Fig. 8a), 54 providing a platform for enantioselective sensing of chiral molecules. The CD intensity of ( S , R )-C10 at 250 nm decreased with increasing concentration of d -carvone (Fig.…”

Porous organic cages for gas separations

“…44 Since then, there has been a rapid increase in the number of POCs with different topologies, shapes, and surface areas, attracting significant attention over the past decade. 45–73 The common methods used to synthesize POCs can be categorized into two types: irreversible bond formation and reversible bond formation, which mainly include several condensation reactions. 20 Both methods have been extensively reviewed in recent publications.…”

Helical Cage Rotors Switched on by Brake Molecule with Variable Fluorescence and Circularly Polarized Luminescence

“…So far, the explorations of CPL performance of molecular cages are mainly focused on the chirality induction using chiral species in the molecular states. ,− The CPL activity in the aggregation states seldom refers to cage molecules . Also, the manipulation of the CPL performance of cages by achiral factors is scarcely reported.…”

“…Fujita et al have constructed a homologous series of coordination molecular cages with different-sized cavities to selectively enclose one or two dye molecules, realizing the accuracy control of monomeric, excimer, and charge-transfer luminescence in solution . Therefore, luminescent molecular cages would be suitable candidates for CPL materials while an appropriate chiral elements was rationally incorporated in them. ,− However, in comparison with ordinary small organic molecules or coordination supramolecular molecules, it is still a great challenge to effectively couple emissive and chiral elements in one cage-type molecule, and consequently, the study of CPL performance of molecular cages is still in its infancy.…”