Enantioselective Addition of Phenyl and Alkyl Acetylenes to Imines Catalyzed by Chiral Cu(I) Complexes.

Abstract

Amines Q 0120Enantioselective Addition of Phenyl and Alkyl Acetylenes to Imines Catalyzed by Chiral Cu (I) Complexes. -The enantioselective addition of terminal alkynes to bisarylimines is efficiently catalyzed by Cu(I) complexes of binaphthyl based chiral bis-imine ligand. Best results are obtained under the conditions shown. -(BENAGLIA*, M.; NEGRI, D.; DELL'ANNA, G.; Tetrahedron Lett. 45 (2004) 47, 8705-8708; Dip. Chim. Org. Ind., Univ. Stud. Milano, CNR, I-20133 Milano, Italy; Eng.) -Mais 09-061