Enantioselective [3 + 2] annulation of tryptanthrin-derived ketimines and 2-naphthols: access to polycyclic indolo[2,1-b]quinazoline derivatives

Abstract

A highly enantioselective [3 + 2] annulation of tryptanthrine-derived ketimines and 2-naphthols with chiral phosphoric acid as a catalyst has been established. This method allows access to a series of...