1992
DOI: 10.1002/mcs.1220040305
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Enantiomeric resolution of dansyl amino acids by microcolumn liquid chromatography with γ‐cyclodextrin as a mobile phase additive

Abstract: Abstract. Enantiomeric resolution of dansyl amino acids by microcolumn liquid chromatography with y-cyclodextrin as a mobile phase additive has been investigated. The separation factor for the enantiomers increased with increasing ycyclodextrin concentration as well as with decreasing acetonitrile concentration in the mobile phase. The present method was successful for the resolution of twelve dansyl amino acid enantiomeric pairs.

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Cited by 6 publications
(1 citation statement)
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“…Three approaches can be employed to solve this task: separations on chiral columns [98]; separations on achiral stationary phases with mobile phases containing chiral selectors [98,99]; precolumn derivatization with chiral agents (e.g., enantiomers of P-methyl amino acid-containing peptides can be separated after derivatization with 1-fluoro-2,4-dinitrophenyl-5-L-alanine amide and 2,3,4,6-tetra-O-acetyl-P-D-glucopyranosyl isothiocyanate [loo]).…”
Section: Chiral Separationsmentioning
confidence: 99%
“…Three approaches can be employed to solve this task: separations on chiral columns [98]; separations on achiral stationary phases with mobile phases containing chiral selectors [98,99]; precolumn derivatization with chiral agents (e.g., enantiomers of P-methyl amino acid-containing peptides can be separated after derivatization with 1-fluoro-2,4-dinitrophenyl-5-L-alanine amide and 2,3,4,6-tetra-O-acetyl-P-D-glucopyranosyl isothiocyanate [loo]).…”
Section: Chiral Separationsmentioning
confidence: 99%