Enamines in Heterocyclic Synthesis: Route to Aminopyrazolopyrimidines and Arylpyrazolopyrimidiens Derivatives

Medrasi, Hanadi Y.; Salaheldin, Abdellatif M.

doi:10.11648/j.mc.20140201.11

Cited by 16 publications

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Recent Progress in Materials Chemistry to Advance Flexible Bioelectronics in Medicine

et al. 2022

View full text Add to dashboard Cite

Designing bioelectronic devices that seamlessly integrate with the human body is a technological pursuit of great importance. Bioelectronic medical devices that reliably and chronically interface with the body can advance neuroscience, health monitoring, diagnostics, and therapeutics. Recent major efforts focus on investigating strategies to fabricate flexible, stretchable, and soft electronic devices, and advances in materials chemistry have emerged as fundamental to the creation of the next generation of bioelectronics. This review summarizes contemporary advances and forthcoming technical challenges related to three principal components of bioelectronic devices: i) substrates and structural materials, ii) barrier and encapsulation materials, and iii) conductive materials. Through notable illustrations from the literature, integration and device fabrication strategies and associated challenges for each material class are highlighted.

show abstract

Recent Progress in Materials Chemistry to Advance Flexible Bioelectronics in Medicine

et al. 2022

View full text Add to dashboard Cite

show abstract

Effects of ultrasonic cavitation on neutralization process of low molecular weight polyethylene glycol

et al. 2018

View full text Add to dashboard Cite

In recent decades, ultrasound has been broadly employed in different applications, particularly in the chemical industry. Ultrasound enhances chemical reactions in a solution via generation of cavitation microbubbles. It improves mass transfer rate and kinetic rate of targeted systems under various process conditions. In polyethylene glycol (PEG) production, the neutralization reaction is generally carried out by employing a mechanical stirring operation. However, this process produces a soluble salt containing potassium and acetate ions, which are known to appreciably manipulate/alter the properties of PEG. In this paper, ultrasound influence is initially analyzed through the neutralization of deionized water. This study then focuses on the neutralization of PEG using ultrasonic cavitation and its impact on the properties of PEG. The ultrasonic cavitation unit employed in this research is a COLE‐Parmer® 500 W & 20 kHz with an ultrasonic probe. To investigate the efficiency of the ultrasonic cavitation reactor and analyze the important aspects of the implemented method, the concentration of soluble salts and conductivity of PEG neutralized by the ultrasonic cavitation method are measured and compared with those of the commercial PEG prepared by the mechanical stirring methodology. The results reveal that the neutralization reaction via the ultrasonic cavitation lowers the conductivity and concentrations of potassium and acetate ions, compared to the traditional stirring methods. It is also concluded that the minimum conductivity and the minimum content of potassium and acetate ions are achieved at 30 % power and a reaction time of 5 min. This study promises the efficient utilization of the ultrasonic cavitation in the industrial sectors, particularly in pharmaceutical industries.

show abstract

Poly(ethylene glycol)s as Ligands in Calcium‐Catalyzed Cyclic Carbonate Synthesis

Steinbauer

Werner

2017

ChemSusChem

View full text Add to dashboard Cite

Herein the use of CaI in combination with poly(ethylene glycol) dimethyl ether (PEG DME 500) as an efficient catalyst system for the addition of CO to epoxides is reported. This protocol is based on a nontoxic and abundant metal in conjunction with a polymeric ligand. Fifteen terminal epoxides were converted at room temperature to give the desired products in yields up to 99 %. Notably, this system was also effective for the synthesis of twelve challenging internal carbonates in yields up to 98 %.

show abstract

Enamines in Heterocyclic Synthesis: Route to Aminopyrazolopyrimidines and Arylpyrazolopyrimidiens Derivatives

Cited by 16 publications

References 24 publications

Recent Progress in Materials Chemistry to Advance Flexible Bioelectronics in Medicine

Recent Progress in Materials Chemistry to Advance Flexible Bioelectronics in Medicine

Effects of ultrasonic cavitation on neutralization process of low molecular weight polyethylene glycol

Poly(ethylene glycol)s as Ligands in Calcium‐Catalyzed Cyclic Carbonate Synthesis

Contact Info

Product

Resources

About