Enalapril‐lercanidipine combination induced leukocytoclastic vasculitis: A case report

Cutaneous leukocytoclastic vasculitis associated with verapamil and atorvastatin: A case report

“…Calcium channel blockers and statins have been rarely associated with leukocytoclastic vasculitis, with only a few case reports in the literature. [2][3][4][5][6] Of calcium channel blockers, only diltiazem, 3 lercarnidipine, 4 and amlodipine 5 have been implicated. We present a case of leukocytoclastic vasculitis associated with atorvastatin and verapamil.…”

“…1 Leukocytoclastic vasculitis is a small-vessel vasculitis predominantly affecting dermal capillaries and venules, and often secondary to underlying systemic vasculitis, infection or drug exposure. 1 Commonly implicated drugs include beta-lactam antibiotics and non-steroidal anti-inflammatory drugs, 1 while calcium channel blockers and hydroxymethylglutaryl-coA reductase inhibitors (statins) have been rarely associated [2][3][4][5][6] -with no previous formal case report for verapamil. We present a case of cutaneous leukocytoclastic vasculitis associated with recently initiated verapamil and atorvastatin.…”

Cutaneous leukocytoclastic vasculitis associated with verapamil and atorvastatin: A case report

“…Calcium channel blockers and statins have been rarely associated with leukocytoclastic vasculitis. A literature search of PubMed and Google Scholar using the terms “leukocytoclastic vasculitis”, “cryoglobulin”, “calcium channel blocker” “verapamil”, “statin” and “atorvastatin” yielded only a few similar case reports 2–6 . Among the calcium channel blockers, only diltiazem, 3 lercarnidipine, 4 and amlodipine 5 have been implicated.…”

“… 1 Leukocytoclastic vasculitis is a small‐vessel vasculitis predominantly affecting dermal capillaries and venules, and often secondary to underlying systemic vasculitis, infection, or drug exposure. 1 Commonly implicated drugs include beta‐lactam antibiotics and nonsteroidal anti‐inflammatory drugs, 1 while calcium channel blockers and hydroxymethylglutaryl‐coA reductase inhibitors (statins) have been rarely associated 2 , 3 , 4 , 5 , 6 —with no previous formal case report for verapamil. We present a case of cutaneous leukocytoclastic vasculitis associated with recently initiated verapamil and atorvastatin.…”

Leukocytoclastic vasculitis induced by lercanidipine

“…Concerning LER, only one previous case of an enalapril-LER combination induced LCV was reported (10). But, no cases are available on drug-induced LCV associated with LER only.…”