Emulsions Stabilized with Alumina-Functionalized Mesoporous Silica Particles

Dechézelles, Jean-François; Ciotonea, Carmen; Catrinescu, Cezar; Ungureanu, Adrian; Royer, Sébastien; Nardello‐Rataj, Véronique

doi:10.1021/acs.langmuir.9b03900

Cited by 10 publications

(4 citation statements)

References 45 publications

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“…This trend is associated with the possible blockage of a part of the mesopores in supports when Al content increases as well as the 2 times higher density of alumina phase with respect of silica [38]. A decrease in the microporous surface area is observed upon Al deposition, as already reported [41,42]. A comparable evolution is observed for the pore volume, which decreases by 25% and 55 for low Al-loading Pd/Al40-SBA, respectively.…”

Section: Catalyst Characterizationsupporting

confidence: 76%

Hydrodeoxygenation of m-cresol over Pd/Al-SBA-15 catalysts: Effect of Al content on the deoxygenation reaction pathways

Teles

Ciotonea

Gomes

et al. 2022

Applied Catalysis A: General

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Section: Catalyst Characterizationsupporting

confidence: 76%

Hydrodeoxygenation of m-cresol over Pd/Al-SBA-15 catalysts: Effect of Al content on the deoxygenation reaction pathways

Teles

Ciotonea

Gomes

et al. 2022

Applied Catalysis A: General

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“…However, incomplete drug release and toxic bioaccumulation phenomenon of MSNs limit their clinical applications. Recently, researchers have proposed methodological strategies, such as reconfiguring silica nanoparticle structures by organic-inorganic hybridization and metal ion doping [21] , to improve the biodegradation properties of MSNs. Academician Shi Jianlin's group at the Shanghai Institute of Silicate Research prepared MSNs doped with manganese ions and organic fragments by sol-gel [20] and hydrothermal methods [23] , respectively, and successfully achieved rapid degradation of MSNs in the tumor microenvironment (TME), and also significantly improved the therapeutic effect and the resolution of MRI-weighted images.…”

Section: Introductionmentioning

confidence: 99%

Preparation of Ca-Mg double-doped mesoporous silica nanoparticles and their drug-loading and drug-releasing properties

Zhang,

Huang,

Liu

et al. 2024

Preprint

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Objective: To prepare Doxorubicin-loaded Ca-Mg double-doped mesoporous silica nanoparticles (Ca-Mg@SiO2@DOX) and examine their properties. Methods: Mesoporous silica nanoparticles (MSNs) and Ca-Mg@SiO2 nanoparticles were prepared by hydrothermal method and evaluated for particle size, zeta potential, morphology, and elemental distribution. SiO2@DOX nanoparticles and Ca-Mg@SiO2@DOX nanoparticles were prepared by electrostatic adsorption to investigate their properties, such as particle size, zeta potential, encapsulation efficiency, drug loading, stability, release degree, biosafety, and in vitro antitumor property. Results: MSNs and SiO2@DOX nanoparticles were successfully prepared with a particle size of about 200-300 nm and negatively charged; the MSNs and SiO2@DOX nanoparticles were regular spherical, and the Ca and Mg doped nanoparticles showed irregular spherical shape, and mapping measured the Ca and Mg elements contains were 2.92% and 1.19% respectively. SiO2@DOX nanoparticles and Ca-Mg@SiO2@DOX nanoparticles were successfully prepared with a particle size of about 300-400 nm, also negatively charged, encapsulation efficiency of about 90%, and a drug loading efficiency of 10%, with a slower release compared to DOX of solution. The release of Ca-Mg@SiO2@DOX nanoparticles was faster in an acid condition. All samples’ hemolysis efficiency was less than 5%. Cellular toxicity showed that SiO2@DOX nanoparticles and Ca-Mg@SiO2@DOX nanoparticles are toxic to lower than free DOX. Living and dead cell staining experiments showed similar situations. Cell uptake showed that cell uptake is higher compared with free DOX Ca-Mg@SiO2@DOX nanoparticles. Conclusion: We successfully prepared Ca-Mg@SiO2@DOX nanoparticles, which have a suitable particle size, zeta potential, and stability, which are released faster in acid conditions, which can reduce the toxicity of DOX, boost cell uptake, and have good antitumor properties.

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“…The colloidal particles used so far for Pickering stabilization include those made from modified natural or synthetic polymers 15,16 and inorganic particles. 17 However, the growing preference for label-friendly ingredients, particularly in foodstuffs, 18 has increased the demand for new choices, 19 T h i s c o n t e n t i s expanding the interest in other particle stabilizers, especially if derived from natural and renewable resources. 14 Among the latter, plant-based particles are promising candidates, 20,21 owing to their abundance, sustainability, biodegradability, and nontoxicity.…”

Section: ■ Introductionmentioning

confidence: 99%

Pickering Emulsions via Interfacial Nanoparticle Complexation of Oppositely Charged Nanopolysaccharides

Huan

Zhu

et al. 2021

ACS Appl. Mater. Interfaces

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We consider the variables relevant to adsorption of renewable nanoparticles and stabilization of multiphase systems, including particle's hydrophilicity, electrostatic charge, axial aspect, and entanglement. Exploiting the complexation of two oppositely charged nanopolysaccharides, cellulose nanofibrils (CNF) and nanochitin (NCh), we prepared CNF/NCh aqueous suspensions and identified the conditions for charge balance (turbidity and electrophoretic mobility titration). By adjusting the composition of CNF/NCh complexes close to net neutrality, we produced sunflower oil-in-water Pickering emulsions with adjustable 2 droplet diameter and stability against creaming and oiling-off. The adsorption of CNF/NCh complexes at the oil/water interface occurred with simultaneous partitioning (accumulation) of CNF on the surface of the droplets in net negative or positive systems (below and above stochiometric charge balance relative to NCh). We further show that the morphology of the droplets and size distribution were preserved during storage for at least 6-months at ambient conditions. This long-term stability was held with a remarkable tolerance to changes in pH (e.g., 3 ~ 11) and ionic strength (e.g., 100 ~ 500 mM). The mechanism explaining these observations relates to the adsorption of CNF in the complexes, counteracting the charge losses resulting from the deprotonation of NCh or charge screening. Overall, CNF/NCh complexes and the respective interfacial nanoparticle exchange greatly extend the conditions favoring highly stable, green Pickering emulsions that offer potential in applications relevant to foodstuff, pharmaceutical, and cosmetic formulations .

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Emulsions Stabilized with Alumina-Functionalized Mesoporous Silica Particles

Cited by 10 publications

References 45 publications

Hydrodeoxygenation of m-cresol over Pd/Al-SBA-15 catalysts: Effect of Al content on the deoxygenation reaction pathways

Hydrodeoxygenation of m-cresol over Pd/Al-SBA-15 catalysts: Effect of Al content on the deoxygenation reaction pathways

Preparation of Ca-Mg double-doped mesoporous silica nanoparticles and their drug-loading and drug-releasing properties

Pickering Emulsions via Interfacial Nanoparticle Complexation of Oppositely Charged Nanopolysaccharides

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