Empleo de leche de cabra en pacientes con alergia a las proteínas de la leche de vaca

Pina, D. Infante; Carnicé, Ramon Tormo; Zandueta, M. Conde

doi:10.1016/s1695-4033(03)78737-2

Cited by 20 publications

(7 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…There is increasing interest with respect to the suitability of non-cattle milks as a hypoallergenic option to cattle milk (74). A few studies have reported that horse milk (75), donkey milk (76,77), camel milk (78,79), and water buffalo milk (80) may be potential alternatives in cases of moderate allergenicity to cattle milk in children; however, this needs to be further investigated because weak cross-reactivity of non-cattle milk proteins with cattle milk proteins has been reported (81)(82)(83). Jenkins et al (71) conducted a comprehensive study on the cross-reactivity of human and non-human milk proteins and found that the (13).…”

Section: Hypoallergenic Potential Of Non-cattle Milksmentioning

confidence: 99%

“…Infante et al (84) reported that 25% of patients had a negative immunological test for adverse reactions to goat milk proteins; thus, goat milk cannot be considered to be a suitable alternative in cases of cattle milk allergy. Similarly, there is also strong evidence of allergenicity or positive cross-reactivities of goat, sheep, deer, and buffalo milk with cattle milk (83,(85)(86)(87). In addition, reports concerning selective allergy to goat and sheep milk proteins, but not to cattle milk proteins, are also available (88,89).…”

Section: Hypoallergenic Potential Of Non-cattle Milksmentioning

confidence: 99%

See 1 more Smart Citation

Composition, Structure, and Digestive Dynamics of Milk From Different Species—A Review

et al. 2020

View full text Add to dashboard Cite

Background: The traditional dairy-cattle-based industry is becoming increasingly diversified with milk and milk products from non-cattle dairy species. The interest in non-cattle milks has increased because there have been several anecdotal reports about the nutritional benefits of these milks and reports both of individuals tolerating and digesting some non-cattle milks better than cattle milk and of certain characteristics that non-cattle milks are thought to share in common with human milk. Thus, non-cattle milks are considered to have potential applications in infant, children, and elderly nutrition for the development of specialized products with better nutritional profiles. However, there is very little scientific information and understanding about the digestion behavior of non-cattle milks. Scope and Approach: The general properties of some non-cattle milks, in comparison with human and cattle milks, particularly focusing on their protein profile, fat composition, hypoallergenic potential, and digestibility, are reviewed. The coagulation behaviors of different milks in the stomach and their impact on the rates of protein and fat digestion are reviewed in detail. Key findings and Conclusions: Milk from different species vary in composition, structure, and physicochemical properties. This may be a key factor in their different digestion behaviors. The curds formed in the stomach during the gastric digestion of some non-cattle milks are considered to be relatively softer than those formed from cattle milk, which is thought to contribute to the degree to which non-cattle milks can be easily digested or tolerated. The rates of protein and fat delivery to the small intestine are likely to be a function of the macro- and micro-structure of the curd formed in the stomach, which in turn is affected by factors such as casein composition, fat globule and casein micelle size distribution, and protein-to-fat ratio. However, as no information on the coagulation behavior of non-cattle milks in the human stomach is available, in-depth scientific studies are needed in order to understand the impact of compositional and structural differences on the digestive dynamics of milk from different species.

show abstract

Section: Hypoallergenic Potential Of Non-cattle Milksmentioning

confidence: 99%

Section: Hypoallergenic Potential Of Non-cattle Milksmentioning

confidence: 99%

Composition, Structure, and Digestive Dynamics of Milk From Different Species—A Review

et al. 2020

View full text Add to dashboard Cite

show abstract

“…Donkey’s milk (DM) has recently received growing interest as has been reported to be an adequate alternative for children with CMPA and CM-FPIES, mainly due to its nutritional similarities with human milk [23] and excellent palatability and tolerability [24–29], unlike the milk of other species, such as goat’s and sheep’s milk, which can lead to cross-reactivity between their proteins and CM proteins [17, 30, 31]. In fact, DM shows a protein fraction more similar to HM than CM, in addition to which, the primary structure of DM’s caseins presents significant differences compared to other species, and it is always more closely related with HM counterparts [18, 32–34].…”

Section: Introductionmentioning

confidence: 99%

Donkey’s Milk in the Management of Children with Cow’s Milk protein allergy: nutritional and hygienic aspects

et al. 2019

View full text Add to dashboard Cite

Background The therapeutic strategy for children with cow’s milk allergy (CMA) consists in the elimination of cow’s milk (CM) from their diet. Donkey’s milk (DM) has been reported to be an adequate alternative, mainly to his nutritional similarities with human milk (HM) and excellent palatability. The aim of present prospective study was to evaluate the nutritional impact of DM on the diet of children with CMA in term of children growth. Methods Before the nutritional trial on children and during the study the health and hygiene risks and nutritional and nutraceuticals parameters of DM were monitored. Children with CMA were identified by the execution of in vivo and in vitro tests for CM and subsequent assessment of tolerability of DM with oral food challenge (OFC). Finally, we prescribed DM to a selected group of patients for a period of 6 months during which we monitored the growth of children. A total of 81 children, 70 with IgE mediated cow’s milk protein allergy (IgE-CMPA) and 11 with Food Protein Induced Enterocolitis Syndrome to CM (CM-FPIES), were enrolled. Results Seventy-eight out of 81 patients underwent the OFC with DM and only one patient with IgE-CMPA (1.5 %) reacted. Twenty-two out of 81 patients took part of the nutritional trial. All the 22 patients took and tolerated the DM, moreover DM did not change the normal growth rate of infants. Conclusions In conclusion, DM resulted safe in term of health and hygiene risks and nutritionally adequate: no negative impact on the normal growth rate of children was assessed. Therefore, it may be a suitable alternative for the management of IgE mediated CMA and FPIES, also in the first 6 months of life, if adequately supplemented.

show abstract

Section: Can Milk Lipids Mediate the Development Of Allergies?mentioning

confidence: 99%

“…To date, there have been only animal studies or small clinical studies in pediatric populations providing some evidence for a role of goat milk in the reduction of allergy risk in infancy [99][100][101]. Some children previously sensitised to cow milk showed less severe reactions to goat milk [99,102]. The development of allergy involves several mechanisms, and, while the type of proteins may underlie the differential response to goat and cow milk, the role of proteins will not be covered in this review.…”

Section: Can Milk Lipids Mediate the Development Of Allergies?mentioning

confidence: 99%

Whole Goat Milk as a Source of Fat and Milk Fat Globule Membrane in Infant Formula

2020

View full text Add to dashboard Cite

Cow milk is the most common dairy milk and has been extensively researched for its functional, technological and nutritional properties for a wide range of products. One such product category is infant formula, which is the most suitable alternative to feed infants, when breastfeeding is not possible. Most infant formulas are based on cow milk protein ingredients. For several reasons, consumers now seek alternatives such as goat milk, which has increasingly been used to manufacture infant, follow-on and young child formulas over the last 30 years. While similar in many aspects, compositional and functional differences exist between cow and goat milk. This offers the opportunity to explore different formulations or manufacturing options for formulas based on goat milk. The use of whole goat milk as the only source of proteins in formulas allows levels of milk fat, short and medium chain fatty acids, sn-2 palmitic acid, and milk fat globule membrane (MFGM) to be maximised. These features improve the composition and microstructure of whole goat milk-based infant formula, providing similarities to the complex human milk fat globules, and have been shown to benefit digestion, and cognitive and immune development. Recent research indicates a role for milk fat and MFGM on digestive health, the gut–brain axis and the gut–skin axis. This review highlights the lipid composition of whole goat milk-based infant formula and its potential for infant nutrition to support healthy digestion, brain development and immunity. Further work is warranted on the role of these components in allergy development and the advantages of goat milk fat and MFGM for infant nutrition and health.

show abstract

Empleo de leche de cabra en pacientes con alergia a las proteínas de la leche de vaca

Cited by 20 publications

References 7 publications

Composition, Structure, and Digestive Dynamics of Milk From Different Species—A Review

Composition, Structure, and Digestive Dynamics of Milk From Different Species—A Review

Donkey’s Milk in the Management of Children with Cow’s Milk protein allergy: nutritional and hygienic aspects

Whole Goat Milk as a Source of Fat and Milk Fat Globule Membrane in Infant Formula

Contact Info

Product

Resources

About