Theory and research suggest that maternal psychological characteristics are a significant variable in the infant weight gain during childhood, while fewer studies have examined the role of fathers' psychological profiles. Being the family relationship a core aspect of interpersonal processes during the developmental age, the evaluation of directly and indirectly involved variables in infants and in their parents is a key aim. Both maternal and paternal characteristics can impact on children's weight faltering and psychological functioning, so that it would be useful to considerate the fathers' role as risk or protective factor. The present study aimed to evaluate the impact of maternal psychological functioning on the child's adaptation during childhood, considering the paternal involvement in caregiving. Participants were N=60 parents with their children, recruited through nurseries and primary schools in Central Italy, longitudinally assessed in 6 years, when children were 2 (Time 1), 5 (Time 2) and 8 years old (Time 3). Children with severe feeding difficulties tend to have mothers with similar problems, whereas paternal psychopathology reveals a relevant role in the quality of caregiving modulating the interactional mother-infant patterns. Assessment of maternal and paternal psychopathological risk appears to be crucial to deal with the failure to thrive in their children and for promotion of early intervention in this field. We can say that the involvement of fathers can reduce the impact of important maternal difficulties on infant's wellbeing, promoting an overall positive balance of the family.