Emotional memory modulation in schizophrenia: an overview

Dieleman, Sieds; Röder, Constantin

doi:10.1111/acps.12047

Cited by 16 publications

(18 citation statements)

References 102 publications

(123 reference statements)

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“…Previous research (Herbener, 2008; Dieleman and Röder, 2013) suggests the facilitative effect of emotional valence on memory is more often preserved in SZ on tasks involving intentional encoding, shorter delays, and stronger emotional stimuli. Comparatively, our study utilized an incidental task, a 24 hour delay, and excluded extreme images.…”

Section: Discussionmentioning

confidence: 88%

Associations between trait anhedonia and emotional memory deficits in females with schizophrenia versus major depression

Olsen

Bjorkquist

Bodapati

et al. 2015

Psychiatry Research

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Individuals with schizophrenia (SZ) and individuals with major depressive disorder (MDD) demonstrate impaired emotional memory and decreased enjoyment of pleasant experiences (e.g., anhedonia). However, it is unclear whether these impairments reflect similar or different processes in the two diagnostic groups. This study compared emotional memory performance in three groups of females – controls, MDD, and SZ. Given that physical and social trait anhedonia has been shown to differentiate course of illness and emotional functioning within each disorder, the present study also examined whether trait anhedonia related to emotional memory differently in the groups. Participants viewed emotional and neutral images and twenty-four hours later completed an incidental recognition test. SZ participants demonstrated a trend for the worst memory performance. Across all groups, high intensity and negative images were remembered most accurately, while groups were not differentially influenced by the valence of the stimuli. Physical anhedonia was predictive of reduced memory for negative stimuli across all diagnostic groups. Group specific findings indicated that higher levels of social anhedonia were predictive of poorer memory, but only in the SZ group. Effects remained significant when controlling for depressive symptoms. Results are considered in light of the differing role of anhedonia in SZ and MDD.

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Section: Discussionmentioning

confidence: 88%

Associations between trait anhedonia and emotional memory deficits in females with schizophrenia versus major depression

Olsen

Bjorkquist

Bodapati

et al. 2015

Psychiatry Research

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show abstract

“…Individuals with schizophrenia show impairments in several reward processing subcomponents that involve applying cognitive operations to rewarding stimuli. These include disturbances in long‐term memory for rewarding/pleasurable experiences, reward learning and prediction error processing, the representation and maintenance of reward value within working memory, decision making concerning effort costs associated with obtaining rewards, and anticipation/prospection for future rewards. Impairments in these areas are often, though not always, related to clinical ratings of motivational negative symptoms (e.g., anhedonia, asociality).…”

Section: Recent Developments and Future Directions For Research On Comentioning

confidence: 99%

Nonsocial and social cognition in schizophrenia: current evidence and future directions

2019

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Cognitive impairment in schizophrenia involves a broad array of nonsocial and social cognitive domains. It is a core feature of the illness, and one with substantial implications for treatment and prognosis. Our understanding of the causes, consequences and interventions for cognitive impairment in schizophrenia has grown substantially in recent years. Here we review a range of topics, including: a) the types of nonsocial cognitive, social cognitive, and perceptual deficits in schizophrenia; b) how deficits in schizophrenia are similar or different from those in other disorders; c) cognitive impairments in the prodromal period and over the lifespan in schizophrenia; d) neuroimaging of the neural substrates of nonsocial and social cognition, and e) relationships of nonsocial and social cognition to functional outcome. The paper also reviews the considerable efforts that have been directed to improve cognitive impairments in schizophrenia through novel psychopharmacology, cognitive remediation, social cognitive training, and alternative approaches. In the final section, we consider areas that are emerging and have the potential to provide future insights, including the interface of motivation and cognition, the influence of childhood adversity, metacognition, the role of neuroinflammation, computational modelling, the application of remote digital technology, and novel methods to evaluate brain network organization. The study of cognitive impairment has provided a way to approach, examine and comprehend a wide range of features of schizophrenia, and it may ultimately affect how we define and diagnose this complex disorder.

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“…This deficit influences psychosocial functioning and quality of life and is only minimally influenced by antipsychotic medications [9]. General processing of positive and negative expressions in schizophrenia appears to be differentially altered, and especially, negative emotion exerts a considerable influence on cognitive impairments [7].…”

Section: Introductionmentioning

confidence: 99%

Emotional effect on cognitive control in implicit memory tasks in patients with schizophrenia

2015

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The aim of this study was to reveal a potential effect of emotion on cognitive control in the implicit memory task with emotionally neutral and unpleasant words in healthy controls and patients with schizophrenia using a 3.0 T functional MRI (fMRI). A total of 15 patients with schizophrenia and 15 healthy controls underwent the fMRI. fMRI data were obtained while the participants performed the implicit memory tasks with emotionally neutral and unpleasant words. During the implicit memory retrieval with emotionally neutral words, the predominant activation areas observed in patients in contrast to healthy controls included the precuneus, superior parietal gyrus, and dorsolateral prefrontal cortex (dlPFC). In the implicit memory retrieval with unpleasant words, patients with schizophrenia showed dominant activities in the superior and middle temporal gyri, fusiform gyrus, supramarginal gyrus, postcentral gyrus, occipital gyrus, lingual gyrus, parahippocampal gyrus, amygdala, and insula as well as precuneus, superior parietal gyrus, and dlPFC. Blood-oxygen-level-dependent signal changes in the dlPFC were correlated positively with the scores of the negative symptoms under the PANSS during implicit memory retrieval with unpleasant words in patients with schizophrenia. These findings would be useful to understand the neural mechanisms related to general impairment of cognitive and emotional functions commonly observed in schizophrenia.

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Emotional memory modulation in schizophrenia: an overview

Abstract: Deficits in EMM in long-term compared to short-term memory point toward impaired emotional modulation of memory consolidation. Reduced EMM on implicit, but not explicit, tasks suggests a deficit in unconsciously using emotional content to modulate memory.

Cited by 16 publications

References 102 publications

Associations between trait anhedonia and emotional memory deficits in females with schizophrenia versus major depression

Associations between trait anhedonia and emotional memory deficits in females with schizophrenia versus major depression

Nonsocial and social cognition in schizophrenia: current evidence and future directions

Emotional effect on cognitive control in implicit memory tasks in patients with schizophrenia

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