Emission Spectroscopy

Scribner, Bourdon F.

doi:10.1021/ac50163a008

Cited by 7 publications

(2 citation statements)

References 64 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…While advances in EI gaseous ion spectrometry continued throughout the late 1940's, the incompatibility of MS with liquid analyses limited the widespread adoption of the technique. 27 In many ways the advancement of MS stalled, as other analytical techniques were considered less troublesome. 28 It required the commercial introduction of gas chromatography in the early 1950's to renew interest in MS as a chromatographic detector 29 .…”

Section: Equation 8 Representation Of Gas Phase Electron Ionizationmentioning

confidence: 99%

High Resolution Mass Spectrometry (HRMS) Based Investigation of Small Molecule, Bioactive Secondary Metabolites as Probes in the Examination of Bacterial Resistance and Virulence

Scarborough¹

View full text Add to dashboard Cite

The widespread availability of antimicrobial chemotherapeutics over the last half of the twentieth century has offered dramatic increases in life expectancy. Unfortunately, many pathogenic agents are exhibiting ever increasing resistance to many frontline antibiotics. New chemotherapeutic agents are urgently needed to combat this threat; this work seeks to illustrate applications in which mass spectrometric techniques may be applied to the investigation of novel, small molecule chemotherapeutics for the treatment of bacterial infections. Chapter 1 contains an introduction to mass spectrometry, as well as an overview of relevant chromatographic techniques. Chapter 2 introduces the bacterium F tularensis and M ulcerans and details the MS based investigation of their secreted virulence factors. Chapter 3 introduces a human pathogen of particular concern, M tuberculosis, and contains a detailed reporting on the MS based investigation of internally synthesized compounds for the treatment of latent Tb. vii TABLE OF CONTENTS CHAPTER 1. INTRODUCTION TO MASS SPECTROMETERY .

show abstract

Section: Equation 8 Representation Of Gas Phase Electron Ionizationmentioning

confidence: 99%

High Resolution Mass Spectrometry (HRMS) Based Investigation of Small Molecule, Bioactive Secondary Metabolites as Probes in the Examination of Bacterial Resistance and Virulence

Scarborough¹

View full text Add to dashboard Cite

show abstract

“…The versatility of the direct-reading spectroscopic tech nique in analysis of a wide range of sample types is well documented in the literature. Numerous papers on quality control in steel and metal production methods (18)(19)(20)(21)(22)(23)(24)(25)(26)(27)(28)(29)(30), appli cation to agricultural problems (31) and review articles on applications (32)(33)(34)(35)(36)(37) and instrumentation (38)(39)(40)(41)(42)(43)(44) have been published within the last two decades.…”

mentioning

confidence: 99%