“…For example, thanks to ALMA it has been possible to detect new molecules such as cyclic C 3 H 2 (Qi et al 2013b; Bergin et al 2016), CH 3 CN (Öberg et al 2015), and CH 3 OH (Walsh et al 2016), and to image the CO snowline in a few disks (Mathews et al 2013; Qi et al 2013c, 2015; Schwarz et al 2016; Zhang et al 2017). Infrared (IR) observations using space telescopes such as Spitzer and ground-based facilities such as the Very Large Telescope (VLT) and the Keck Observatory telescopes have provided a view of the molecular content of the very inner regions of protoplanetary disks, where absorption and emission lines from molecules such as CO, CO 2 , H 2 O, OH, HCN, C 2 H 2 , and CH 4 have been routinely observed (Lahuis et al 2006; Gibb et al 2007; Salyk et al 2007, 2008, 2011; Carr & Najita 2008, 2011, 2014; Pontoppidan et al 2010a,b; Najita et al 2010, 2013; Kruger et al 2011; Doppmann et al 2011; Fedele et al 2011; Mandell et al 2012; Bast et al 2013; Gibb & Horne 2013; Sargent et al 2014; Banzatti et al 2017). The launch of the Herschel Space Observatory was also very helpful to investigate the chemical content at far-IR wavelengths, with the detection of molecules such as CH + (Thi et al 2011) and NH 3 (Salinas et al 2016), and the exhaustive characterization of H 2 O and OH from the inner to the outer regions (Hogerheijde et al 2011; Riviere-Marichalar et al 2012; Meeus et al 2012; Fedele et al 2012, 2013; Podio et al 2013).…”