Emerging trends and research foci of neuromyelitis optica spectrum disorder: a 20-year bibliometric analysis

Abstract

BackgroundNeuromyelitis optica spectrum disorder (NMOSD) is a demyelinating syndrome of the central nervous system. A tremendous amount of literature on NMOSD has been published. This study aimed to perform a bibliometric analysis of the publications on NMOSD and show its hotspots and development trends.MethodsWe used the Web of Science Core Collection as a database and searched the literature published between 2002 and 2022. CiteSpace, VOSviewer, online bibliometric platform, and R-bibliometrix were used to conduct bibliometric analysis and network visualization, including the number of publications, citations, countries/regions, institutions, journals, authors, references, and keywords.ResultsA total of 3,057 publications on NMOSD were published in 198 journals by 200 authors at 200 institutions from 93 countries/regions. The United States published the most literature and made great contributions to this field. The Mayo Clinic was the institution with the largest number of publications. The journal with the most publications was Multiple Sclerosis and Related Disorders, and the most co-cited journal was Neurology. The author with the most publications was Fujihara, K., while the most frequently co-cited author was Wingerchuk, DM. The current research hotspots may be focused on “efficacy,” “multicenter,” “interleukin-6 receptor blockade,” “safety,” “azathioprine,” “tolerance,” and “adult”.ConclusionThis study was the first bibliometric analysis of publications on the NMOSD field, visualizing its bibliometric characteristics and gaining insight into the direction, hotspots, and development of global NMOSD research, which may provide helpful information for researchers. Future research hotspots might be conducting randomized controlled trials on targeted immunotherapy in the NMOSD field.

Global trends and research status in ankylosing spondylitis clinical trials: a bibliometric analysis of the last 20 years

“…The articles in this study were indexed from the Web of Science Core Collection (WoSCC) database, which contains more than 10,000 journals and is one of the most commonly used and authoritative databases for bibliometric analysis ( 16 ). The search strategy used was as follows ( 17 ): TI = (“Spondyloarthritis Ankylopoetica*”) OR TI = (“Ankylosing Spondylitis*”) OR TI = (“Ankylosing Spondylarthritis*”) OR TI= (“Spondylarthritis Ankylopoetica*”) OR TI= (“Spondyloarthritides, Ankylosing*”) OR TI= (“Ankylosing Spondyloarthritis*”) OR TI= (“Ankylosing Spondyloarthritides*”) OR TI= (“Spondylitis Ankylopoetica*”).…”