Emerging therapies for the treatment and prevention of otitis media

Aliphas, Avner; Prufer, Neil; Grundfast, Kenneth M.

doi:10.1517/14728214.11.2.251

Cited by 4 publications

(3 citation statements)

References 81 publications

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“…13,14 A particu-lar concern is the inappropriate use of antibiotics that do not have long-term efficacy and are not recommended for routine OME management 7 and may lead to antibiotic resistance. [15][16][17][18][19] The goal of this article was to highlight issues for developing and testing measures of quality of care for children with OME based on our experience with a set of measures for OME in a sample of general pediatric practices.…”

Section: Introductionmentioning

confidence: 99%

Quality Measures for the Care of Children With Otitis Media With Effusion

2011

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Section: Introductionmentioning

confidence: 99%

Quality Measures for the Care of Children With Otitis Media With Effusion

2011

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“…1) [13,14]. AOM occurs in almost all children, and epidemiological data suggest that, by three years of age, 75-80% of children will have had at least one episode, with the peak incidence occurring before the age of two years [2,15,16].…”

Section: Global Burden Of Ommentioning

confidence: 99%

Challenges in reducing the burden of otitis media disease: An ENT perspective on improving management and prospects for prevention

Grevers¹

2010

International Journal of Pediatric Otorhinolaryngology

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Acute otitis media (AOM) is a major public health concern. This frequent disease of childhood is a leading cause of physician visits, a major component of paediatric healthcare burden, and a key contributor to antibiotic resistance. An international expert group comprising mainly ear, nose, and throat physicians met in June 2008 to discuss the optimal management of AOM, particularly with regards to unmet needs in diagnosis and management. Current guidelines do not help identify which patients are most at risk for severe or complicated AOM. Diagnosis of AOM is also complicated by a lack of correlation between clinical signs and symptoms and responsible pathogens. Consequently, treatment of AOM is not always appropriate, and the long-term overuse of antibiotics in AOM reduces the effectiveness of treatment and places children at risk for drug-resistant infections. There is a need for educational and research initiatives to improve diagnostic accuracy and management of AOM. Because there is currently no ideal treatment, vaccination is an attractive additional approach for managing AOM and reducing its burden.

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“…Previous studies focused on prevention through chemoprophylaxis, vaccination programs, therapy with new types of antibiotics and improvement of surgical techniques (4). Options for surgical therapy include myringotomy and adenoidectomy.…”

Section: Introductionmentioning

confidence: 99%

Acute otitis media in children: Correlation with palatine tonsil size, adenoidectomy and adenotonsillectomy

et al. 2014

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Objective -The objective of the survey was to assess the role and importance of the hypertrophy of palatine tonsils and previously performed adenoidectomy and adenotonsillectomy for the incidence of the acute otitis media in children. Materials and methods -The prospective and controlled study was carried out among 160 patients of both genders, aged between 6 months and 7 years, with an acute otitis media, during a 12-month period. The control group consisted of 40 examinees who had not been diagnosed with this disease. Clinical assessment of the palatine tonsil size was performed according to the degree of obstruction of the isthmus faucium: hypertrophy -grade I (both palatine tonsils obstruct up to ½ of the isthmus faucium), and hypertrophy -grade II (both palatine tonsils obstruct more than ½ of the isthmus faucium). Patients were stratified by age into three groups: 3 -11 months, 1 -2.5 years and 2.6 -7 years. The association between antibiotic therapy and new cases of adenotonsillar infections was evaluated. Follow-up audiological examinations were conducted. The study was carried out on the basis of a questionnaire survey. Results -Adenoidectomy was performed in 8.3% of examinees with acute otitis media, adenotonsillectomy in 7.5%, while 84.2% of examinees were not treated with any of the above mentioned surgical procedures. No statistically significant differences were found compared to the control group (p=0,213). The palatine tonsils were eutrophic in 26.8% of the examinees with the acute otitis media, 55.4% had hypertrophy -grade I, and 17.9% hypertrophy -grade II. The differences between the observed groups were statistically significant (p=0.019). ConclusionThe hypertrophy of palatine tonsils was statistically significantly more prevalent in examinees with acute otitis media compared with the control group. This kind of level of significance was not recorded regarding previously performed adenoidectomy and adenotonsillectomy.

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Emerging therapies for the treatment and prevention of otitis media

Cited by 4 publications

References 81 publications

Quality Measures for the Care of Children With Otitis Media With Effusion

Quality Measures for the Care of Children With Otitis Media With Effusion

Challenges in reducing the burden of otitis media disease: An ENT perspective on improving management and prospects for prevention

Acute otitis media in children: Correlation with palatine tonsil size, adenoidectomy and adenotonsillectomy

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