Emerging roles of vascular brassinosteroid receptors of the BRI1-like family

Lozano-Elena, Fidel; Caño‐Delgado, Ana I.

doi:10.1016/j.pbi.2019.06.006

Cited by 21 publications

(17 citation statements)

References 67 publications

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“…A Convergence of Systemic Signals? Our results highlight the emerging importance of brassinosteroid perception in the vasculature [64] and add to a growing literature that demonstrates that different classes of hormone signals target distinct tissue types to control growth of roots [65,66]. Interestingly, among them, an inverse scenario to ours has been reported previously, that is, the induction of a severe systemic root growth defect by engineered tissue-specific disruption of gibberellin perception [67,68].…”

Section: Brassinosteroid Signaling Has Distinct Local and Systemic Roles In The Protophloemsupporting

confidence: 84%

Local and Systemic Effects of Brassinosteroid Perception in Developing Phloem

et al. 2020

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Section: Brassinosteroid Signaling Has Distinct Local and Systemic Roles In The Protophloemsupporting

confidence: 84%

Local and Systemic Effects of Brassinosteroid Perception in Developing Phloem

et al. 2020

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“…MP promotes the switch to floral fate in Arabidopsis 52 and the tomato ortholog of TFL1 executes its role in inflorescence architecture at least in part by modulating auxin flux and response 53 . Finally, we identified key components of the brassinosteroid pathway including the BRI1 receptor and the bHLH transcription factor BIM1 54 , 55 as direct TFL1–FD complex repressed targets. Brassinosteroid signalling represses inflorescence branching in Setaria 56 .…”

Section: Resultsmentioning

confidence: 99%

TERMINAL FLOWER 1-FD complex target genes and competition with FLOWERING LOCUS T

et al. 2020

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Plants monitor seasonal cues to optimize reproductive success by tuning onset of reproduction and inflorescence architecture. TERMINAL FLOWER 1 (TFL1) and FLOWERING LOCUS T (FT) and their orthologs antagonistically regulate these life history traits, yet their mechanism of action, antagonism and targets remain poorly understood. Here, we show that TFL1 is recruited to thousands of loci by the bZIP transcription factor FD. We identify the master regulator of floral fate, LEAFY (LFY) as a target under dual opposite regulation by TFL1 and FT and uncover a pivotal role of FT in promoting flower fate via LFY upregulation. We provide evidence that the antagonism between FT and TFL1 relies on competition for chromatin-bound FD at shared target loci. Direct TFL1-FD regulated target genes identify this complex as a hub for repressing both master regulators of reproductive development and endogenous signalling pathways. Our data provide mechanistic insight into how TFL1-FD sculpt inflorescence architecture, a trait important for reproductive success, plant architecture and yield.

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“…Besides, this study mainly focuses on the suppressor lines of bri1–5 . Future work by adding enhancer lines such as bri1–5/bri1–1 , bri1–5/brs1–1 , and bri1–5/bak1–1 or by studying the effect of suppressors not only in the BRI1 as a loss-of-function background but also using double or triple mutants of multiple genes of the BRI1 gene family and/or BRI1 -like genes [ 52 ] could be interesting to further elucidate the mechanism of BRI signaling. In addition, future research by scRNA-seq of bri1–5 suppressor mutants across different time points of hypocotyl growth would be key to elucidating the detailed mechanisms of BR signaling at the level of cell types [ 53 , 54 ].…”

Section: Discussionmentioning

confidence: 99%

Genome-wide expression and network analyses of mutants in key brassinosteroid signaling genes

et al. 2021

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Background Brassinosteroid (BR) signaling regulates plant growth and development in concert with other signaling pathways. Although many genes have been identified that play a role in BR signaling, the biological and functional consequences of disrupting those key BR genes still require detailed investigation. Results Here we performed phenotypic and transcriptomic comparisons of A. thaliana lines carrying a loss-of-function mutation in BRI1 gene, bri1–5, that exhibits a dwarf phenotype and its three activation-tag suppressor lines that were able to partially revert the bri1–5 mutant phenotype to a WS2 phenotype, namely bri1–5/bri1–1D, bri1–5/brs1–1D, and bri1–5/bak1–1D. From the three investigated bri1–5 suppressors, bri1–5/bak1–1D was the most effective suppressor at the transcriptional level. All three bri1–5 suppressors showed altered expression of the genes in the abscisic acid (ABA signaling) pathway, indicating that ABA likely contributes to the partial recovery of the wild-type phenotype in these bri1–5 suppressors. Network analysis revealed crosstalk between BR and other phytohormone signaling pathways, suggesting that interference with one hormone signaling pathway affects other hormone signaling pathways. In addition, differential expression analysis suggested the existence of a strong negative feedback from BR signaling on BR biosynthesis and also predicted that BRS1, rather than being directly involved in signaling, might be responsible for providing an optimal environment for the interaction between BRI1 and its ligand. Conclusions Our study provides insights into the molecular mechanisms and functions of key brassinosteroid (BR) signaling genes, especially BRS1.

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Emerging roles of vascular brassinosteroid receptors of the BRI1-like family

Cited by 21 publications

References 67 publications

Local and Systemic Effects of Brassinosteroid Perception in Developing Phloem

Local and Systemic Effects of Brassinosteroid Perception in Developing Phloem

TERMINAL FLOWER 1-FD complex target genes and competition with FLOWERING LOCUS T

Genome-wide expression and network analyses of mutants in key brassinosteroid signaling genes

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