Emerging persistent chemicals in human biomonitoring for populations in the Arctic: A Canadian perspective

Gibson, Jennifer C.

doi:10.1016/j.scitotenv.2019.134538

Cited by 12 publications

(4 citation statements)

References 34 publications

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“…The results of the study made it possible to draw certain conclusions and proposals. Environmental and legal problems of reclamation and development of the Arctic region require a systematic approach [10][11][12]. International law plays a special role in correlation with environmental law to regulate social relations in the development of the Arctic territories.…”

Section: Discussionmentioning

confidence: 99%

Correlation of branches of law in environmental and legal support of the development of the Arctic region

et al. 2021

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The purpose of the study is to analyze individual independent branches of law included in environmental law and their variability in determining special approaches to the development of the Arctic in modern geopolitical conditions. The methodological basis of the research includes the general scientific method and special methods of cognition, such as comparative legal, environmental legal, statistical and empirical. The results of the study are the conclusions from the analysis of the main program and legal documents regulating the development and development of the territories of the Arctic states. Moreover, the attempts to create an adequate system of convergence of national and international legal regulation in order to determine the modern legal regime of the Arctic are discussed herein. The study of international and domestic experience has shown the need for a correlation of individual branches of law (international, administrative, criminal, informational) with the environmental law to provide comprehensive environmental and legal support for the development of the Arctic region. The authors also draw attention to the fact that environmental and legal problems of the development of the Arctic region require a systematic approach. The novelty of the study lies in the conclusion that, despite the fact that each state of the Arctic region has a national strategy for the development of its Arctic territory, on most topical issues these strategies are of a similar nature and have common approaches: scientifically based methods of managing the natural resources of the Arctic region; special methods of socio-economic development; preservation of vulnerable Arctic ecological systems and scientific activities in the field of climate change.

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Section: Discussionmentioning

confidence: 99%

Correlation of branches of law in environmental and legal support of the development of the Arctic region

et al. 2021

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“…Since the mid-20th century, we have seen an increasing and rapid expansion of biomonitoring population studies in various countries and continents, such as the United States, Europe, and Canada [28], to measure a growing number of chemicals in ever larger groups of participants. A wide range of environmental exposure has been investigated, from historic pollution, such as lead [29,30], to synthetic chemicals, including pesticides [12,[31][32][33], to new emerging chemicals [12,34,35]. Hence, HBM is rapidly becoming a key means of providing a scientific basis for prevention via exposure reduction and motivating action.…”

Section: The Role Of Human Biomonitoring In Chemical Trespassmentioning

confidence: 99%

Health and Psychological Concerns of Communities Affected by Per- and Poly-Fluoroalkyl Substances: The Case of Residents Living in the Orange Area of the Veneto Region

Menegatto,

Zamperini

2023

IJERPH

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Residents of an extensive area of the Veneto Region (Italy) face one of the largest technological disasters due to per- and polyfluoroalkyl substances (PFAS). On the basis of a risk gradient of contamination, the affected territories were divided into 4 areas: Red (of maximum exposure, where a human biomonitoring programme (HBM) was activated), Orange, Yellow, and Green. This article presents a case study of residents who live in the Orange Area, the second area in terms of contamination, excluded from the HBM. Semi-structured interviews were conducted with 17 residents engaged in promoting a legal procedure to exercise their right to know. Grounded theory and a thematic analysis method were used. Overall, the findings revealed that experiencing contamination causes a negative psychosocial impact on the residents’ lives; difficulty accessing information; living with uncertainty, caused by the lack of institutional and health support and medical consultation; a sense of abandonment; difficulty managing preventive and protective actions; and the deterioration of relationships, on the basis of the social comparison with residents of the Red Area, to whom HBM was granted and where the concept of health ostracism has emerged. This study demonstrated that biomonitoring may help reduce discomfort in the case of contamination by informing people of their chemical exposure.

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“…However, the levels of legacy AHSs in the Baltic Sea region have stopped declining rapidly in recent years [3,[6][7][8][9]. Furthermore, new industrial chemicals that may potentially be of concern are produced every year [3,4,10]. Therefore, it is important to develop tools for assessing exposure to AHSs, the overall health of organisms in the ecosystem, and the state of key physiological processes.…”

Section: Supplementary Informationmentioning

confidence: 99%

Non-targeted screening workflows for gas chromatography–high-resolution mass spectrometry analysis and identification of biomagnifying contaminants in biota samples

Rebryk

Haglund

2020

Anal Bioanal Chem

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The health of key species in the Baltic region has been impaired by exposure to anthropogenic hazardous substances (AHSs), which accumulate in organisms and are transferred through food chains. There is, thus, a need for comprehensive characterization of the occurrence and accumulation of AHSs in the ecosystem. In this study, we use a non-target screening (NTS) approach for this purpose. A major challenge in NTS of biological samples is the removal of matrix components such as lipids that may interfere with the detection and identification of compounds of interest. Here, we combine gel permeation chromatography with Florisil® column fractionation to achieve sufficient lipid removal for gas chromatography–high-resolution mass spectrometry analysis using electron ionization (EI) and electron capture negative ion chemical ionization (ECNI). In addition, we present new data processing workflows designed to systematically find and identify frequently occurring and biomagnifying AHSs, including known, emerging, and new contaminants. Using these workflows, we discovered a wide range of contaminants in tissue samples from blue mussels, fish, and marine mammals, and calculated their biomagnification factors (BMFs). Compounds with BMFs above 1 for herring and at least one marine mammal included legacy chlorinated pollutants (polychlorinated biphenyls, DDTs, chloro-benzenes/cyclohexanes, chlordanes, toxaphenes, dieldrin), polybrominated diphenyl ethers (PBDEs), and brominated biphenyls. However, there were also several halogenated natural products (halogenated methoxylated brominated diphenyl ethers, 1′-methyl-1,2′-bipyrroles, 1,1′-dimethyl-2,2′-bipyrroles, and the halogenated monoterpene mixed halogenated compound 1) as well as the novel flame retardant Dechlorane 602 and several polycyclic aromatic hydrocarbons, terpenoids, and steroids. The legacy pollutants exhibited the expected biomagnification behavior, demonstrating the utility of the unguided data processing workflow.

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Emerging persistent chemicals in human biomonitoring for populations in the Arctic: A Canadian perspective

Cited by 12 publications

References 34 publications

Correlation of branches of law in environmental and legal support of the development of the Arctic region

Correlation of branches of law in environmental and legal support of the development of the Arctic region

Health and Psychological Concerns of Communities Affected by Per- and Poly-Fluoroalkyl Substances: The Case of Residents Living in the Orange Area of the Veneto Region

Non-targeted screening workflows for gas chromatography–high-resolution mass spectrometry analysis and identification of biomagnifying contaminants in biota samples

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