“…The rapid progress of clinic biomedicine and nanobiotechnology has stimulated the generation of diverse novel inorganic nanosystems, which offers multiple theranostic modalities as potential alternatives in combating various diseases by synergistic therapy and multimodal imaging, especially in cancer theranostics 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11. Currently, great efforts for multidisciplinary research have been focused on biomedical applications of 2D nanomaterials, a newly emerging subtype of nanomaterials with ultrathin layer‐structured topology, including mostly explored graphene and its derivatives,12, 13 hexagonal boron nitrides (h‐BN),14 transition metal dichalcogenides (TMDCs),15 transition metal oxides (TMOs),16 palladium (Pd) nanosheets,17 black phosphorus (BP),18, 19 and transition metal carbides (MXenes) 20.…”