Emerging Nanomaterials for Cancer Targeting and Drug Delivery

Pandian, Sureshbabu Ram Kumar; Panneerselvam, Theivendren; Ravishankar, Vigneshwaran; Pavadai, Parasuraman; Sivakumar, Vellaichamy; Palanisamy, Ponnusamy; Murugesan, Sankaranarayanan; Kunjiappan, Selvaraj

doi:10.1007/978-3-030-82918-6_14

Cited by 2 publications

(2 citation statements)

References 136 publications

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“…While planning ternary structures, a few factors that focus on moiety must be considered to produce a viable conveyance framework. To begin with, a cell receptor and its ligand must have characteristics that qualify them as tumor-explicit targets ( 141 ). For instance, the receptor should be produced excessively in disease cells, not normal cells.…”

Section: Tumor Targeting Of Lbnpsmentioning

confidence: 99%

Lipid-based nanoparticles as drug delivery carriers for cancer therapy

Waheed,

Ali,

Tabassum

et al. 2024

Front. Oncol.

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Cancer is a severe disease that results in death in all countries of the world. A nano-based drug delivery approach is the best alternative, directly targeting cancer tumor cells with improved drug cellular uptake. Different types of nanoparticle-based drug carriers are advanced for the treatment of cancer, and to increase the therapeutic effectiveness and safety of cancer therapy, many substances have been looked into as drug carriers. Lipid-based nanoparticles (LBNPs) have significantly attracted interest recently. These natural biomolecules that alternate to other polymers are frequently recycled in medicine due to their amphipathic properties. Lipid nanoparticles typically provide a variety of benefits, including biocompatibility and biodegradability. This review covers different classes of LBNPs, including their characterization and different synthesis technologies. This review discusses the most significant advancements in lipid nanoparticle technology and their use in medicine administration. Moreover, the review also emphasized the applications of lipid nanoparticles that are used in different cancer treatment types.

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Section: Tumor Targeting Of Lbnpsmentioning

confidence: 99%

Lipid-based nanoparticles as drug delivery carriers for cancer therapy

Waheed,

Ali,

Tabassum

et al. 2024

Front. Oncol.

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“…Receptors are generally located on cell membrane which allows specific drug carrier interaction with cells ingested by means of re ceptor mediated endocytosis (RME) [72]. The folate receptors in the cancer cells which are overly expressed are useful for drug de livery in cancer including malignancies in lung, brain, ovary, and breast [73]. Moreover, peptide receptor is expressed in high amount in some tumor cells which results into the conjugation of a peptide to drug carriers, thus allowing precise targeting of cyto toxic substance with decent interaction with the receptors [74].…”

Section: Receptormentioning

confidence: 99%

Nanomedicines: A Focus on Nanomaterials as Drug Delivery System with Current Trends and Future Advancement

et al. 2022

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The rapid advancement of nanomedicine presents novel alternatives that have the potential to transform health care. Targeted drug delivery as well as the synthesis of nanocarriers is a growing discipline that has been intensively researched to reduce the complexity of present medicines in a variety of diseases and to develop new treatment and diagnostic techniques. There are several designed nanomaterials used as a delivery system such as liposomes, micelles, dendrimers, polymers, carbon-based materials, and many other substances, which deliver the drug moiety directly into its targeted body area reducing toxic effect of conventional drug delivery, thus reducing the amount of drug required for therapeutic efficacy and offering many more advantages. Currently, these are used in many applications, including cancer treatment, imaging contrast agents, and biomarker detection and so on. This review provides a comprehensive update in the field of targeted nano-based drug delivery systems, by conducting a thorough examination of the drug synthesis, types, targets, and application of nanomedicines in improving the therapeutic efficiency.

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Emerging Nanomaterials for Cancer Targeting and Drug Delivery

Cited by 2 publications

References 136 publications

Lipid-based nanoparticles as drug delivery carriers for cancer therapy

Lipid-based nanoparticles as drug delivery carriers for cancer therapy

Nanomedicines: A Focus on Nanomaterials as Drug Delivery System with Current Trends and Future Advancement

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