Emerging MAP kinase pathways in plant stress signalling

Nakagami, Hirofumi; Pitzschke, Andrea; Hirt, Heribert

doi:10.1016/j.tplants.2005.05.009

Cited by 607 publications

(482 citation statements)

References 84 publications

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“…The relevance of the MAPK signaling pathway for salt tolerance has been well established in Arabidopsis (Mizoguchi et al, 1996;Ichimura et al, 2000;Teige et al, 2004;Nakagami et al, 2005), whereas in rice relatively little is known. A MAPK module typically consists of three protein kinases: MAP3K, MAP2K, and MAPK.…”

Section: Discussionmentioning

confidence: 99%

“…MAPKs phosphorylate a Ser or Thr residue that is followed by a Pro residue (Nakagami et al, 2005). Five Ser residues and one Thr residue are conserved among SERF1 and its homologs (see Supplemental Figure 1 online).…”

Section: Phosphorylation Of Serf1 Increases Its Ability To Activate Tmentioning

confidence: 99%

“…Likewise, MAPK5 confers enhanced tolerance to salt and osmotic stress when overexpressed (Xiong and Yang, 2003). In Arabidopsis, a MAPK module consisting of MEKK1-MKK2-MPK4/MPK6 was found to regulate salt tolerance (Nakagami et al, 2005). Moreover, the mkk2 mutant exhibits a salt-sensitive phenotype (Teige et al, 2004).…”

Section: Introductionmentioning

confidence: 99%

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SALT-RESPONSIVE ERF1 Regulates Reactive Oxygen Species-Dependent Signaling during the Initial Response to Salt Stress in Rice

et al. 2013

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Early detection of salt stress is vital for plant survival and growth. Still, the molecular processes controlling early salt stress perception and signaling are not fully understood. Here, we identified SALT-RESPONSIVE ERF1 (SERF1), a rice (Oryza sativa) transcription factor (TF) gene that shows a root-specific induction upon salt and hydrogen peroxide (H 2 O 2 ) treatment. Loss of SERF1 impairs the salt-inducible expression of genes encoding members of a mitogen-activated protein kinase (MAPK) cascade and salt tolerance-mediating TFs. Furthermore, we show that SERF1-dependent genes are H 2 O 2 responsive and demonstrate that SERF1 binds to the promoters of MAPK KINASE KINASE6 (MAP3K6), MAPK5, DEHYDRATION-RESPONSIVE ELEMENT BINDING2A (DREB2A), and ZINC FINGER PROTEIN179 (ZFP179) in vitro and in vivo. SERF1 also directly induces its own gene expression. In addition, SERF1 is a phosphorylation target of MAPK5, resulting in enhanced transcriptional activity of SERF1 toward its direct target genes. In agreement, plants deficient for SERF1 are more sensitive to salt stress compared with the wild type, while constitutive overexpression of SERF1 improves salinity tolerance. We propose that SERF1 amplifies the reactive oxygen species-activated MAPK cascade signal during the initial phase of salt stress and translates the salt-induced signal into an appropriate expressional response resulting in salt tolerance.

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Section: Discussionmentioning

confidence: 99%

Section: Phosphorylation Of Serf1 Increases Its Ability To Activate Tmentioning

confidence: 99%

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SALT-RESPONSIVE ERF1 Regulates Reactive Oxygen Species-Dependent Signaling during the Initial Response to Salt Stress in Rice

et al. 2013

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“…A current challenge in this research area is to determine which signaling pathways in the plant make use of which MAPK components. Recent reviews have summarized our current understanding of the roles of plant MAPK pathways in cell division, development, and stress responses (Tena et al, 2001;Jonak et al, 2002;Nakagami et al, 2005).…”

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confidence: 99%

MEKK1 Is Required for flg22-Induced MPK4 Activation in Arabidopsis Plants

et al. 2006

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The Arabidopsis (Arabidopsis thaliana) gene MEKK1 encodes a mitogen-activated protein kinase kinase kinase that has been implicated in the activation of the map kinases MPK3 and MPK6 in response to the flagellin elicitor peptide flg22. In this study, analysis of plants carrying T-DNA knockout alleles indicated that MEKK1 is required for flg22-induced activation of MPK4 but not MPK3 or MPK6. Experiments performed using a kinase-impaired version of MEKK1 (K361M) showed that the kinase activity of MEKK1 may not be required for flg22-induced MPK4 activation or for other macroscopic FLS2-mediated responses. MEKK1 may play a structural role in signaling, independent of its protein kinase activity. mekk1 knockout mutants display a severe dwarf phenotype, constitutive callose deposition, and constitutive expression of pathogen response genes. This dwarf phenotype was largely rescued by introduction into mekk1 knockout plants of either the MEKK1 (K361M) construct or a nahG transgene that degrades salicylic acid. When treated with pathogenic bacteria, the K361M plants were slightly more susceptible to an avirulent strain of Pseudomonas syringae and showed a delayed hypersensitive response, suggesting a role for MEKK1 kinase activity in this aspect of plant disease resistance. Our results indicate that MEKK1 acts upstream of MPK4 as a negative regulator of pathogen response pathways, a function that may not require MEKK1's full kinase activity.

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“…These mechanisms are involved in many aspects of anatomy, physiology, biochemistry, genetics, development, evolution, and molecular biology, in which the adaptive machinery related to molecular biology, is the most important . The elucidation of it will extremely and purposefully promote the sustainable utilization of plant resources and make the best use of its current potential at different scales [27,28,[34][35][36][37][38][39][40][41][42][43]. This molecular mechanism at least includes environmental signal recognition (input), signal transduction (many cascade biochemical reactions are involved in this process), signal output, signal responses and phenotype realization, which is a multi-dimension network system and contains many levels of gene expression and regulation [43][44][45][46][47][48][49][50][51][52][53].…”

Section: Introductionmentioning

confidence: 99%

The responding relationship between plants and environment is the essential principle for agricultural sustainable development on the globe

Zhou

Shao

2008

Comptes Rendus. Biologies

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The mutual-responding relationship between plants and environment is involved in all life processes, which are the essential bases for different types of sustainable development on the globe, particularly the critical basis for agricultural sustainable development. How to regulate the above relationship between plants and the corresponding environment (in particular soil environment) is the key problem to modern sustainable agriculture development under global climate change, which is one of the hot topics in the field of plant biology. Detailed dissection of this responding relationship is also important for conducting global eco-environmental restoration and construction. Although powerful methodology and dataset related to genomics, post-genomics, and metabolomics have provided some insights into this relationship, crop physiological measures are also critical for crop full performance in field. With the increase of tested plants (including model plants) and development of integrated molecular biology, a complete understanding of the relationship at different scales under biotic and abiotic stresses will be accelerated. In the current paper, we will cover some important aspects in combination with the recent work from our laboratory and related advances reflected by international academic journals, as follows: plant physiological function performance under natural condition, plant gene regulatory network system under abiotic stresses, gene regulatory network system and drought resistance improvement, summary of the related work from our laboratory, conclusions, and acknowledgement.

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Emerging MAP kinase pathways in plant stress signalling

Cited by 607 publications

References 84 publications

SALT-RESPONSIVE ERF1 Regulates Reactive Oxygen Species-Dependent Signaling during the Initial Response to Salt Stress in Rice

SALT-RESPONSIVE ERF1 Regulates Reactive Oxygen Species-Dependent Signaling during the Initial Response to Salt Stress in Rice

MEKK1 Is Required for flg22-Induced MPK4 Activation in Arabidopsis Plants

The responding relationship between plants and environment is the essential principle for agricultural sustainable development on the globe

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