Emerging flexible and wearable physical sensing platforms for healthcare and biomedical applications

Kenry, Kenry; Yeo, Joo Chuan; Lim, Chwee Teck

doi:10.1038/micronano.2016.43

Cited by 422 publications

(237 citation statements)

References 131 publications

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“…[1][2][3][4] Compared to rigid sensors, sensors that are flexible, stretchable, and bendable have shown enormous potential in health monitoring, [5][6][7] soft robotics, [8,9] electronics skins, [10][11][12] and prosthetics. [1][2][3][4] Compared to rigid sensors, sensors that are flexible, stretchable, and bendable have shown enormous potential in health monitoring, [5][6][7] soft robotics, [8,9] electronics skins, [10][11][12] and prosthetics.…”

Section: Wearable Sensorsmentioning

confidence: 99%

“…[34][35][36] Recently, several liquid metals that exist in a fluid state in room temperatures are gaining popularity. [1][2][3][4] Compared to rigid sensors, sensors that are flexible, stretchable, and bendable have shown enormous potential in health monitoring, [5][6][7] soft robotics, [8,9] electronics skins, [10][11][12] and prosthetics. [37] Microfluidic devices based on the liquid metals have therefore been increasingly employed as wearable pressure sensors, [38] strain sensors, [39] temperature sensors, [40] and even more recently as a thermotherapy platform.…”

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confidence: 99%

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Ultrathin and Wearable Microtubular Epidermal Sensor for Real‐Time Physiological Pulse Monitoring

Yeo

et al. 2017

Adv Materials Technologies

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high performance of these sensors, their complicated structures, in many cases, require more expensive and complex production routes, limiting its scalability and reproducibility. [33] Conductive liquids belong to another class of materials suitable for deployment in soft and stretchable sensing platforms. These liquids assume the shape of the microchannels within the soft silicone elastomer due to the weak intermolecular forces of attraction between particles. As such, they are highly patternable and reconfigurable. [34][35][36] Recently, several liquid metals that exist in a fluid state in room temperatures are gaining popularity. Among which, Gallistan and eutectic gallium-indium (eGaIn) are two widely reported electrically conductive liquid metallic alloys that are nontoxic and highly deformable. [37] Microfluidic devices based on the liquid metals have therefore been increasingly employed as wearable pressure sensors, [38] strain sensors, [39] temperature sensors, [40] and even more recently as a thermotherapy platform. [41] However, the macroscopic monolithic film format of microfluidics may not fully meet the requirements of imperceptibility and affect conformability due to many subtle but nonflat topologies on the surface of human skin. Thus, an ultrasensitive tactile sensor that is ultrathin, ultralight, and shape configurable is highly desirable.Here, we report an ultrathin microtubular resistive sensor that is soft, flexible, stretchable, and simple to manufacture. The microtube facilitates the deployment of liquid metallic alloy eGaIn which serves as a thin flexible conduit with excellent electrical conductivity and mechanical deformability. Specifically, by considering the radius and thickness of the microtube, we realize an ultrasensitive liquid-based tactile sensor with high flexibility and durability. The self-sustaining fiber-like shape of the sensor is entirely conformal to human interfaces due to its ability to twist around 3D curvatures and objects. In addition, its tiny footprint of 120 µm in diameter makes it almost imperceptible when worn on bare skin. The results of this work establish an attractive option for imperceptible epidermal healthcare diagnostics and monitoring platform.To achieve sensitive force measurements, we utilize liquid metallic alloy within a tubular structure in a submillimeter regime. Liquid metal core fiber of ≈400 µm inner diameter and ≈100 µm in wall thickness has been previously demonstrated as a strain sensor. [42] However, in our current study, we developed a facile manufacturing strategy to achieve an ultrathin, soft core fiber that was previously unattainable. The fabrication process A flexible, stretchable, soft, and ultrathin wearable microtubular sensor that is highly sensitive to mechanical perturbations is developed. The sensor comprises a unique architecture consisting of a liquid-state conductive element core within a soft silicone elastomer microtube. The microtubular sensor can distinguish forces as small as 5 mN and possesses a high force sensitivity ...

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Section: Wearable Sensorsmentioning

confidence: 99%

mentioning

confidence: 99%

Ultrathin and Wearable Microtubular Epidermal Sensor for Real‐Time Physiological Pulse Monitoring

Yeo

et al. 2017

Adv Materials Technologies

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“…For example, as a new ultra‐high‐density memory technology, resistive random access memories (RRAMs) were extensively studied, but their flexible versions are not yet mature . The challenge comes from the active materials, which need to fulfill the requirements of both electronic performance and wearability . After many years of research on sandwich‐like resistive devices, many organic small molecules, polymers, and inorganic oxides as the active layer were found to exhibit multilevel performance .…”

Section: Introductionmentioning

confidence: 99%

One‐Step Fabrication of Bio‐Compatible Coordination Complex Film on Diverse Substrates for Ternary Flexible Memory

Sun

Zhao

Zhou

et al. 2019

Chemistry A European J

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Recently, resistance random access memories (RRAMs) have been studied extensively, because the demand for information storage is increasing. However, it remains challenging to obtain a flexible device because the active materials involved need to be nontoxic, nonpolluting, distortion‐tolerable, and biodegradable as well adhesive to diverse flexible substrates. In this paper, tannic acid (TA) and an iron ion (FeIII) coordination complex were employed as the active layer in a sandwich‐like (Al/active layer/substrate) device to achieve memory performance. A nontoxic, biocompatible TA‐FeIII coordination complex was synthesized by a one‐step self‐assembly solution method. The retention time of the TA‐FeIII memory performance was up to 15 000 s, the yield up to 53 %. Furthermore, the TA‐FeIII coordination complex can form a high‐quality film and shows stable ternary memory behavior on various flexible substrates, such as polyethylene terephthalate (PET), polyimide (PI), printer paper, and leaf. The device can be degraded by immersing it in vinegar solution. Our work will broaden the application of organic coordination complexes in flexible memory devices with diverse substrates.

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“…If the smart diet recipe can integrated with werable devices, it may suggest suitable recepie to fit customers' current physical health after comparing the status of pressure, heartbeat rate and sleep hours [9].…”

Section: Literature Reviewmentioning

confidence: 99%

A RFID-based JIT Application for Least Waiting Time for Dynamic Smart Diet Customers

Chen

2017

ITM Web Conf.

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Abstract. Waiting in queue is part of everyone's life. A day may include several different waiting in queue. Waiting in line is always a bit of phenomena for a prosperous restaurant at dinner time. How to manage the queues and keep their feet into customers is the operating challenge facing everyone manager. In addition, rising energy costs and growing demand for protection of the environment call for a shorter waiting queue. Thus, we devise a dynamic smart diet App manager to reduce customer waiting time through radio frequency identification (RFID) and just in time (JIT) principle to reduce inventory of restaurant food materials, thereby increasing customer satisfaction and loyalty, and improving revenue and social responsibility.

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Emerging flexible and wearable physical sensing platforms for healthcare and biomedical applications

Cited by 422 publications

References 131 publications

Ultrathin and Wearable Microtubular Epidermal Sensor for Real‐Time Physiological Pulse Monitoring

Ultrathin and Wearable Microtubular Epidermal Sensor for Real‐Time Physiological Pulse Monitoring

One‐Step Fabrication of Bio‐Compatible Coordination Complex Film on Diverse Substrates for Ternary Flexible Memory

A RFID-based JIT Application for Least Waiting Time for Dynamic Smart Diet Customers

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