Emergent Management of Tandem Occlusions in Anterior Circulation Stroke: A Single-Centre Experience

Yu, Mengying; Ma, Yanxing; Ren, Hecheng; Huang, Ying; Yin, Long; Ma, Lin; Wang, Yübo; Luo, Bin; Wang, Zengguang

doi:10.1016/j.wneu.2022.11.040

Cited by 2 publications

(1 citation statement)

References 31 publications

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“…Durable patency of the carotid artery may prevent recurrent intracranial embolisms, hemodynamic insufficiency (resulting in the expansion of the ischemic cerebral territory), carotid artery restenosis or reocclusion, and the shedding of unstable plaque. 4,38,39 In addition, considering that reperfusion is an important predictor of functional outcomes in TLs, 1,40 it has been suggested that the advantage of acute CAS is most likely related to the augmentation of intracranial perfusion. 41 In our analysis, we examined acute CAS as the exposure and used successful reperfusion as the mediating factor.…”

Section: Discussionmentioning

confidence: 99%

Mediation Analysis of Acute Carotid Stenting in Tandem Lesions

Rodriguez Calienes,

Galecio-Castillo,

Petersen

et al. 2024

Neurology

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Background and ObjectivesCurrent evidence suggests that acute carotid artery stenting (CAS) for cervical lesions is associated with better functional outcomes in patients with acute stroke with tandem lesions (TLs) treated with endovascular therapy (EVT). However, the underlying causal pathophysiologic mechanism of this relationship compared with a non-CAS strategy remains unclear. We aimed to determine whether, and to what degree, reperfusion mediates the relationship between acute CAS and functional outcome in patients with TLs.

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