Emergent
emm4
group A
Streptococcus
evidences a survival strategy during interaction with immune effector cells
Chioma M. Odo,
Luis A. Vega,
Piyali Mukherjee
et al.
Abstract:The major gram-positive pathogen group A
Streptococcus
(GAS) is a model organism for studying microbial epidemics as it causes waves of infections. Since 1980, several GAS epidemics have been ascribed to the emergence of clones producing increased amounts of key virulence factors such as streptolysin O (SLO). Herein, we sought to identify mechanisms underlying our recently identified temporal clonal emergence among
emm4
GAS, given that emergent strains di… Show more
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