Emergent Complications Following Donepezil Switchover to Galantamine in Three Cases of Dementia With Lewy Bodies

Increased prudence with the use of neuroleptic agents is essential in DLBs because the use of these agents is associated with physical and cognitive decline and increased mortality. While neuroleptic sensitivity has been reported with the use of both typical and atypical antipsychotic medications, these medications are often necessary for the treatment of psychotic symptoms. Decreases in neuroleptic sensitivity can often be achieved by dose reductions, although neuroleptic discontinuation is sometimes necessary. Cholinesterase inhibitors may be especially useful in the treatment of DLB. Cholinergic deficits are associated with visual hallucinations, and cholinesterase inhibitors often result in resolution of hallucinations, improved cognition, and decreased behavioral disturbances.

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Emergent Complications Following Donepezil Switchover to Galantamine in Three Cases of Dementia With Lewy Bodies

Cited by 4 publications

References 14 publications

Dementia treatment

Dementia treatment

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