Emergency management of autonomic dysreflexia with neurologic complications

Squair, Jordan W.; Phillips, Aaron A.; Harmon, Mark; Krassioukov, Andrei V.

doi:10.1503/cmaj.151311

Cited by 25 publications

(13 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Significant associations were not observed with autonomic dysreflexia symptom burden alone. Autonomic dysreflexia is characterized by transient hypertensive episodes, which have been shown to acutely insult cerebral blood vessels [27,54,55]. Chronic hypertension in ablebodied individuals is strongly associated with cognitive decline, encompassing essentially the entire spectrum of cognitive domains including learning and memory, attention, abstract reasoning, executive function, as well as visuospatial, perceptual and psychomotor abilities [56][57][58].…”

Section: Discussionmentioning

confidence: 99%

Diverse cognitive impairment after spinal cord injury is associated with orthostatic hypotension symptom burden

Nightingale

Zheng

Sachdeva

et al. 2020

Physiology & Behavior

Self Cite

View full text Add to dashboard Cite

Where a licence is displayed above, please note the terms and conditions of the licence govern your use of this document. When citing, please reference the published version. Take down policy While the University of Birmingham exercises care and attention in making items available there are rare occasions when an item has been uploaded in error or has been deemed to be commercially or otherwise sensitive.

show abstract

Section: Discussionmentioning

confidence: 99%

Diverse cognitive impairment after spinal cord injury is associated with orthostatic hypotension symptom burden

Nightingale

Zheng

Sachdeva

et al. 2020

Physiology & Behavior

Self Cite

View full text Add to dashboard Cite

show abstract

“…Spinal cord injury induces hemodynamic instability that threatens survival [1][2][3] , impairs neurological recovery 4,5 , increases cardiovascular disease risk 6,7 , and reduces quality of life 8,9 . Hemodynamic instability in this context is due to the interruption of supraspinal excitatory drive to sympathetic circuits located in the spinal cord 10 , which impedes the natural baroreflex.…”

mentioning

confidence: 99%

Neuroprosthetic baroreflex controls haemodynamics after spinal cord injury

Squair

Gautier

Mahe

et al. 2021

Nature

Self Cite

106

123

View full text Add to dashboard Cite

show abstract

“…Antihypertensive agents are administered as needed [ 18 , 39 ]. Nitroglycerin, hydralazine, captopril, and other agents have been recommended as antihypertensive agents in emergencies [ 10 , 30 , 40 ]. Frequent blood pressure monitoring (every 2–5 min) is important because blood pressure may change rapidly [ 41 ].…”

Section: Discussionmentioning

confidence: 99%

Autonomic dysreflexia associated with cervical spinal cord gliofibroma: case report

et al. 2021

View full text Add to dashboard Cite

Background Autonomic dysreflexia (AD) is an abnormal reflex of the autonomic nervous system normally observed in patients with spinal cord injury from the sixth thoracic vertebra and above. AD causes various symptoms including paroxysmal hypertension due to stimulus. Here, we report a case of recurrent AD associated with cervical spinal cord tumor. Case presentation The patient was a 57-year-old man. Magnetic resonance imaging revealed an intramedullary lesion in the C2, C6, and high Th12 levels. During the course of treatment, sudden loss of consciousness occurred together with abnormal paroxysmal hypertension, marked facial sweating, left upward conjugate gaze deviation, ankylosis of both upper and lower extremities, and mydriasis. Seizures repeatedly occurred, with symptoms disappearing after approximately 30 min. AD associated with cervical spinal cord tumor was diagnosed. Histological examination by tumor biopsy confirmed the diagnosis of gliofibroma. Radiotherapy was performed targeting the entire brain and spinal cord. The patient died approximately 3 months after treatment was started. Conclusions AD is rarely associated with spinal cord tumor, and this is the first case associated with cervical spinal cord gliofibroma. AD is important to recognize, since immediate and appropriate response is required.

show abstract

Emergency management of autonomic dysreflexia with neurologic complications

Cited by 25 publications

References 12 publications

Diverse cognitive impairment after spinal cord injury is associated with orthostatic hypotension symptom burden

Diverse cognitive impairment after spinal cord injury is associated with orthostatic hypotension symptom burden

Neuroprosthetic baroreflex controls haemodynamics after spinal cord injury

Autonomic dysreflexia associated with cervical spinal cord gliofibroma: case report

Contact Info

Product

Resources

About