“…Guidewires are routinely used in the Seldinger technique during central venous catheter placement CVC placement is not innocuous as numerous complications may occur, with varying frequency and severity. 1 Arrhythmias, arterial puncture, pneumothorax, etc., are quite a common scenario and are obvious. Complications involving guidewire insertion like looping, knotting, vascular perforation, fragmentation and embolization are not readily appreciated.…”