Emergency Department Ondansetron Use in Children with Type 1 Diabetes Mellitus and Vomiting

Help! I Have a Patient With Diabetes Who Is Sick!

“…Sometimes anti-emetics such as Promethazine (Phenergan) (0.5 mg/kg every four to six hours) or Ondansetron (Zofran) (4 mg under the age of 12, 8 mg over 12 years old, every eight hours) are recommended (Ackerman et al, 2010;Brink et al, 2014;Dayton & Silverstein, 2016;Leung, Perlman, Rumantir, & Freedman, 2015). However, these medications should be used with caution in children with diabetes because they can mask the symptoms of DKA.…”