“…44,46,48,49,51 However, volume per se might not be the leading factor; several important factors include training, protocols, team expertise, benchmarking, maintaining a low threshold for asking for support. 51,53,68 Health systems focus primarily on improving the health of the population and may align resources to assist referring hospitals through regionalization, 45,[69][70][71][72][73][74][75][76][77] and might be better positioned to accomplish this, as efficiency can be increased by sharing resources and capabilities across facilities. 47,55,[78][79][80] The combination of high-volume ECLS center with an effective and appropriately located retrieval service may balance out certain local deficits.…”