Emergence of Refractory Otomastoiditis Due to Nontuberculous Mycobacteria: Institutional Experience and Review of the Literature

Yeh, Ching-Fa; Tu, Tzong-Yang; Wang, Mao-Che; Chu, Chia-Huei; Huang, Chii-Yuan; Su, Wei‐Juin; Shiao, An‐Suey

doi:10.1093/cid/civ1033

Cited by 17 publications

(19 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This was subsequently confirmed as MAI. Although granuloma is a characteristic histopathologic finding, granulation as seen in our patient has previously been reported in infections with M. marinum , M. abscessus , M. chelonae , M. fortuitum, MAI, and other NTMs . Esophageal mycobacterial diseases could be managed with antibiotics alone or in combination with adjunct surgery (Table ).…”

Section: Discussion and Literature Reviewsupporting

confidence: 52%

Esophageal Mycobacterium avium‐intracellulare infection in a bone marrow transplant patient: Case report and literature review

Hou

Nayak

Pincus

et al. 2018

Transplant Infectious Dis

View full text Add to dashboard Cite

show abstract

Section: Discussion and Literature Reviewsupporting

confidence: 52%

Esophageal Mycobacterium avium‐intracellulare infection in a bone marrow transplant patient: Case report and literature review

Hou

Nayak

Pincus

et al. 2018

Transplant Infectious Dis

View full text Add to dashboard Cite

show abstract

“…Yeh et al . discussed the fact that NTM otomastoiditis with TBO should be suspected in cases of chronic otorrhoea, otalgia and granulation tissue in the ear [ 21 ].…”

Section: Discussionmentioning

confidence: 99%

“…A retrospective case series has reported the rates of granulation tissue (90.9 %), otalgia (31.8 %), facial palsy (9.1 %) and lung involvement (5.4 %). Cases of temporal bone osteomyelitis have been reported, most commonly with the NTM M. abscessus (52.7 % of cases) and M. aviumintracellulare, followed by M. fortuitum [21][22][23]. Three distinct routes have been suggested for the entry of NTM into the middle ear: direct inoculation through perforation of the tympanic membrane or a tympanostomy tube (most common), through the eustachian tube, and direct spread via improperly sterilized surgical instruments [22,23].…”

Section: Discussionmentioning

confidence: 99%

Spectrum of mycobacterial pathogens responsible for head and neck tuberculosis-like presentation

Bala

Kumari

Monga

et al. 2021

Access Microbiology

View full text Add to dashboard Cite

Tuberculosis (TB) of the head and neck can be contained in the lymph nodes, larynx, oropharynx, salivary glands, nose and paranasal sinuses, ear, skin and skull. Head and neck TB presentations are varied in nature and thus difficult to diagnose. The clinical features, radiological findings, microbiological diagnostic modalities, surgical and medical management and outcomes of nine cases of head and neck TB are discussed in detail here, together with a thorough review of the literature. Patients presented with atypical symptoms such as discharging sinus, ear lobule swelling, otitis media, vision loss and facial weakness, long refractory otorrhoea and granulation tissue in the ear canal. We diagnosed tubercular skull base osteomyelitis (one case) and laryngeal tuberculosis (two cases), mastoid tuberculosis (one case) and non-tubercular mycobacterial infection involving the temporal bone (two cases), sino-nasal region (one case), maxilla (one cases) and ear lobule (one case) over a period of 8 months. All patients were managed successfully with a combination of surgery and a well-planned treatment regimen for non-tuberculous mycobacteria (NTM) or anti-tubercular drugs for TB. All had successful outcomes except one patient with tubercular skull base osteomyelitis who expired before the initiation of anti-tubercular therapy (ATT). High clinical suspicion followed by thorough diagnostic work-up for both TB and NTM would enable early diagnosis and complete treatment.

show abstract

“…Recently, we described a case of local temporal bone osteomyelitis caused by granulomatous tuberculous infection [22]. Yeh et al reported that in case of chronic otorrhea, otalgia, and granulation tissue in the ear a diagnosis of otomastoiditis with TBO caused by nontuberculous Mycobacteria should be suspected [23]. The authors concluded that acid-fast stain and mycobacterial culture should be performed in all suspicious cases.…”

Section: Discussionmentioning

confidence: 99%

Clinical Challenges in the Diagnosis and Treatment of Temporal Bone Osteomyelitis

Kornilenko

Ročka

Balseris

et al. 2017

Case Reports in Otolaryngology

View full text Add to dashboard Cite

Temporal bone osteomyelitis is a serious life-threatening condition—a quick and proper diagnosis is needed to start treatment and reduce morbidity and mortality. Changing trends of the disease make a differential diagnosis difficult. To emphasize the importance of a clinical suspicion of this dangerous condition, our experience with three difficult cases is presented. The diagnosis was based on clinical symptoms, otoscopic findings, and findings on computed tomography or magnetic resonance imaging. Neoplasm and granulomatous inflammation were excluded by multiple biopsies. The disease can develop in nondiabetic patients. The disorder might be related to the initial inflammatory process in the middle ear with further direct spreading of infection through defects in the bony walls to deep temporal bone structures. Imaging should be performed early to detect osteolytic lesions of the skull base. Surgery was used for the presence of bone sequestra and infratemporal abscess.

show abstract

Emergence of Refractory Otomastoiditis Due to Nontuberculous Mycobacteria: Institutional Experience and Review of the Literature

Cited by 17 publications

References 34 publications

Esophageal Mycobacterium avium‐intracellulare infection in a bone marrow transplant patient: Case report and literature review

Esophageal Mycobacterium avium‐intracellulare infection in a bone marrow transplant patient: Case report and literature review

Spectrum of mycobacterial pathogens responsible for head and neck tuberculosis-like presentation

Clinical Challenges in the Diagnosis and Treatment of Temporal Bone Osteomyelitis

Contact Info

Product

Resources

About