Emergence of New Risk Factors for causing Hypertension

Team, Editorial

doi:10.15419/jmri.4

Cited by 8 publications

(7 citation statements)

References 14 publications

(13 reference statements)

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“…[ 14 ]. Furthermore, high fat and sugar levels may lead to HTN as well and subsequently preeclampsia [ 21 - 22 ].…”

Section: Discussionmentioning

confidence: 99%

Association of Lipid Profile in Pregnancy with Preeclampsia, Gestational Diabetes Mellitus, and Preterm Delivery

Ghodke¹,

Pusukuru²,

Team³

2017

Cureus

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IntroductionDuring the last two trimesters of pregnancy, glucose is spared (for the foetus), while the concentration of fatty acids in plasma increases, which can create complications like preeclampsia, gestational diabetes mellitus (GDM), and preterm delivery.AimTo study the association of serum lipid levels during the second and third trimesters with the development of pregnancy-associated diseases, such as preeclampsia, GDM, and preterm delivery.Methods and MaterialsThe present study was carried out at MGM Hospital, Navi Mumbai, India. Two hundred antenatal cases from October 2012 to October 2014 were enrolled after giving an informed consent. A lipid profile was recorded for each subject and was later accessed. The lipid profile of the subjects having either GDM, preterm, or preeclampsia was further used to find an association with the individual disorders. Statistical analyses were performed using Statistical Package for Social Sciences (SPSS) version 20 (IBM SPSS Statistics, Armonk, NY). All reported p-values are two-tailed, and confidence intervals were calculated at the 95% level.ResultsIn preeclamptic patients, the mean systolic blood pressure was 151.40 mm/Hg and the mean diastolic blood pressure was 74.03 mm/Hg in the third trimester. In preeclamptic patients, the mean serum triglyceride levels in the second trimester were 204.00 mg/dl, while the mean was 243.20 mg/dl in the third trimester. In GDM patients, the mean serum triglyceride was 214.33 mg/dl in the second trimester, while it was 230.50 mg/dl in the third trimester. In patients with preterm, the mean triglycerides levels were 212.83 mg/dl and 240.16 mg/dl in the second and third trimesters, respectively. In preeclamptic patients, the mean serum cholesterol levels in the second trimester were 210 mg/dl, while in the third trimester, the mean was 243.60 mg/dl. In GDM patients, the mean serum cholesterol was 223.50 mg/dl and 242.83 mg/dl in the second and third trimester, respectively. The mean cholesterol levels in patients with preterm in second and third trimesters were 213.33 mg/dl and 243.66 mg/dl, respectively. Out of the total 200 patients, 168 had no complications, while 20 (10%) had preeclampsia, six (3%) had gestational diabetes mellitus, and the other six {3%} had preterm deliveries.ConclusionAn association between maternal early pregnancy triglyceridaemia and the subsequent risk of preeclampsia, gestational diabetes, and preterm deliveries was observed. The occurrence of preeclampsia, gestational diabetes, and preterm deliveries cannot be predicted based on the values of serum cholesterol, high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and very-low-density lipoprotein cholesterol (VLDL-C). Hence, estimation of lipid profile is strongly recommended during pregnancy to prevent the deleterious effect of hyperlipidaemia associated with pregnancy.

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“…[ 14 ]. Furthermore, high fat and sugar levels may lead to HTN as well and subsequently preeclampsia [ 21 - 22 ].…”

Section: Discussionmentioning

confidence: 99%

Association of Lipid Profile in Pregnancy with Preeclampsia, Gestational Diabetes Mellitus, and Preterm Delivery

Ghodke¹,

Pusukuru²,

Team³

2017

Cureus

Self Cite

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“…Mehta suggested that low levels of Vitamin D, along with sugar and fats, should be considered as new risk factors in causing hypertension [ 14 ]. This article will bring forward the importance of Vitamin D and its role in maintaining blood pressure levels.…”

Section: Introductionmentioning

confidence: 99%

Does Vitamin D Deficiency Lead to Hypertension?

Team¹,

Agarwal²

2017

Cureus

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Hypertension (HTN) or high blood pressure is one of the most chronic and deadliest disorders in the world. There are many risk factors responsible for HTN which include age, race, using tobacco, high salt intake, etc. One of the risk factors we would like to highlight is low vitamin D levels. While there is strong evidence that Vitamin D plays an important role in maintaining bone and muscle health, there has been recent debate regarding its role in hypertension. However, there are many studies that have shown an indirect relation between 25-hydroxyvitamin D serum level and blood pressure. However, we suggest that more studies, especially randomised trials, should be conducted.

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“…Some proposed mechanisms are obesity [44], high dietary glycemic load, insulin resistance, β-cell dysfunction, and inflammation [9]. The high content of rapidly absorbed carbohydrates such as sucrose and highfructose corn syrup in SSBs, in conjunction with the large volume consumed, also may lead to hypertension [10], visceral and ectopic adipose tissue accumulation [11,12], and hepatic lipogenesis elevation [13]. Increased uric acid production and lower levels of the vasodilator Nitric Oxide resulted from sugar are other possible factors [45,46].…”

Section: Discussionmentioning

confidence: 99%

“…Some surveys claimed that sugary beverages contribute to obesity and CVD. They are also supposed to increase insulin resistance, inflammation [9], hypertension [10], adiposity [11,12], and lipogenesis [13,14]. The Framingham Offspring Study demonstrated increased incidence of hypertension after four years consumption of ≥1 serving soft drink/day by 22% [15] and also higher incidences of hypertriglyceridemia and low level of high-density lipoprotein cholesterol (HDL-C) compared with non-consumers [15].…”

Section: Introductionmentioning

confidence: 99%

Sugary beverages are associated with cardiovascular risk factors in diabetic patients

Anari

Amani

Veissi

2019

J Diabetes Metab Disord

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Purpose Sugar-sweetened beverages (SSBs) containing high amount of added sugars have increased over the last decades. Due to increased risk of cardiovascular events in type 2 diabetes mellitus (T2DM) patients, we designed a study to assess the association between SSBs and metabolic syndrome, a collection of cardiovascular risk factors, in these patients. Methods A cross-sectional study was performed on T2DM adults (N = 157). Participants had no serious disease or insulin treatment. SSBs records were obtained from a validated food frequency questionnaire. Metabolic syndrome status was extracted from biochemical and anthropometric measurements. Subjects risk factors were compared based on their usual SSBs consumption. Results About half of participants consumed at least one serving of SSBs (Mean intake: 145.6 mL/d) on a weekly basis. Men and women had a similar SSBs pattern. Demographic and anthropometric characteristics were identical in both groups. Higher SSBs intake (≥ 0.5 vs <0.5 serving/ week) was positively associated with hypertension (

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Emergence of New Risk Factors for causing Hypertension

Cited by 8 publications

References 14 publications

Association of Lipid Profile in Pregnancy with Preeclampsia, Gestational Diabetes Mellitus, and Preterm Delivery

Association of Lipid Profile in Pregnancy with Preeclampsia, Gestational Diabetes Mellitus, and Preterm Delivery

Does Vitamin D Deficiency Lead to Hypertension?

Sugary beverages are associated with cardiovascular risk factors in diabetic patients

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