“…In the PCRO rewiring procedure, we reconnect these isolated nodes to the hubs satisfying the corresponding preferential constraint, which can be roughly regarded as the specialized regulatory centers (i.e., the hub regions) in brain networks to perform global physiological functions among the whole brain system. Furthermore, in a recent contribution ( Qian et al, 2024b ), the PCRO-induced oscillation mode transition from the originally single-mode oscillations to the newly multi-mode oscillations has been confirmed to emerge among the preferentially operated nodes (i.e., the integrated local modules), which we think is beneficial for understanding the complicated global multimodal physiological functions in integrated structural and functional brain networks. More importantly, the probability distributions of the three different types of isolated nodes formed in the PCRO are derived according to the statistical analysis method proposed in this article, based on which the probability distribution of the preferentially operated common leaves is acquired explicitly.…”