Emergence of a Unique Penicillin-Resistant
            <i>Streptococcus pneumoniae</i>
            Serogroup 35 Strain

Stanek, Ronald J.; Maher, Mary B.; Norton, Nancy B.; Mufson, Maurice A.

doi:10.1128/jcm.01620-10

Cited by 4 publications

(3 citation statements)

References 39 publications

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“…Collected samples (soil, marine sediment, plant parts) undergo series of pretreatments to promote the possibility of isolating rare actinomycetes and suppress the growth of often isolated streptomyces [96]. These physical and chemical pretreatments include the use of dry heat, phenol treatments, sucrose gradient centrifugation and sodium dodecyl sulfate treatment [42,97].…”

Section: Isolation Of Rare Actinomycetesmentioning

confidence: 99%

Uncovering the biodiversity and biosynthetic potentials of rare actinomycetes

et al. 2022

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Background Antibiotic resistance is on the rise, and new antibiotic research has slowed in recent years, necessitating the discovery of possibly novel microbial resources capable of producing bioactive compounds. Microbial infections are gaining resistance to existing antibiotics, emphasizing the need for novel medicinal molecules to be discovered as soon as possible. Because the possibilities of isolating undiscovered actinomycetes strains have decreased, the quest for novel products has shifted to rare actinomycetes genera from regular environments or the identification of new species identified in unusual habitats. Main body of the abstract The non-streptomyces actinobacteria are known as rare actinomycetes that are extremely difficult to cultivate. Rare actinomycetes are known to produce a variety of secondary metabolites with varying medicinal value. In this review, we reported the diversity of rare actinomycetes in several habitat including soil, plants, aquatic environment, caves, insects and extreme environments. We also reported some isolation methods to easily recover rare Actinobacteria from various sources guided with some procedures to identify the rare Actinobacteria isolates. Finally, we reported the biosynthetic potential of rare actinomycetes and its role in the production of unique secondary metabolites that could be used in medicine, agriculture, and industry. These microbial resources will be of interest to humanity, as antibiotics, insecticides, anticancer, antioxidants, to mention but a few. Short conclusion Rare actinomycetes are increasingly being investigated for new medicinal compounds that could help to address existing human health challenges such as newly emerging infectious illnesses, antibiotic resistance, and metabolic disorders. The bioactive secondary metabolites from uncommon actinomycetes are the subject of this review, which focuses on their diversity in different habitats, isolation, identification and biosynthetic potentials.

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Section: Isolation Of Rare Actinomycetesmentioning

confidence: 99%

Uncovering the biodiversity and biosynthetic potentials of rare actinomycetes

et al. 2022

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“…Many pretreatments are used such as dry heat, phenol treatments (Hayakawa et al, 2004), sucrose gradient centrifugation (Yamamura et al, 2003), and sodium dodecyl sulfate treatment. These treatments eliminate nonfilamentous bacteria from the samples and suppress fungal growth that in turn promotes the growth of slowgrowing rare Actinobacteria (Stanek et al, 2011).…”

Section: Isolation Of Rare Actinobacteriamentioning

confidence: 99%

Microbiological and molecular insights on rare Actinobacteria harboring bioactive prospective

et al. 2020

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Background: Actinobacteria is as a group of advanced filamentous bacteria. Rare Actinobacteria are of special interest as they are rarely isolated from the environments. They are a major source of important bioactive compounds. Determining the proper strategy for the identification of Actinobacteria harboring biosynthetic gene clusters and producing bioactive molecules is a challenging platform. Methodology: In this review, we discuss a consequence of microbiological and molecular methods for the identification of rare Actinobacteria. In addition to that, we shed light on rare Actinobacteria's significance in antibiotic production. We also clarified molecular approaches for the manipulation of novel biosynthetic gene clusters via PCR screening, fosmid libraries, and Illumina whole-genome sequencing in combination with bioinformatics analysis. Conclusion: Perceptions of the conventional and molecular identification of Actinobacteria were conducted. This will open the door for the genetic manipulation of novel antibiotic gene clusters in heterologous hosts. Also, these conclusions will lead to constructing new bioactive molecules via genetically engineering biosynthetic pathways.

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“…The easiest way to do so is to survey nasopharyngeal colonization in healthy children in the community 14 , 16 . Reports of unique mechanisms of resistance in pneumococci have been emerging in literature from the West 17 . A close watch on antibiotic resistance of S. pneumoniae among nasopharyngeal colonizers in hospitalized children would help monitor the changing pattern under antibiotic pressure in the hospital.…”

mentioning

confidence: 99%

Knowledge of serotype prevalence & burden of invasive pneumococcal disease: A prerequisite to vaccine introduction in the country

Kanungo¹

2015

Indian J Med Res

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Emergence of a Unique Penicillin-Resistant Streptococcus pneumoniae Serogroup 35 Strain

Cited by 4 publications

References 39 publications

Uncovering the biodiversity and biosynthetic potentials of rare actinomycetes

Uncovering the biodiversity and biosynthetic potentials of rare actinomycetes

Microbiological and molecular insights on rare Actinobacteria harboring bioactive prospective

Knowledge of serotype prevalence & burden of invasive pneumococcal disease: A prerequisite to vaccine introduction in the country

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