Embryopathic effects of mercuric salts

Gale, Thomas F.; Ferm, Vergil H.

doi:10.1016/0024-3205(71)90185-8

“…This i s in agreement with other studies that indicated a high tendency toward permeability of the placenta to methylmercury (Pitkin et al, 1975;Suzuki et al, 1971;Koos & Longo, 1976 Kuhnert et al (1981) found the highest concentration of inorganic mercury was in the placenta, suggesting a barrier role, but a significant correlation (r = .62) was also found between the maternal and fetal plasma inorganic mercury levels. Animal data are also in agreement with human observations (Gale & Ferm, 1971;Gale & Hanlon, 1976;Gale, 1981;Holt & Webb, 1986). It has been recently reported that exposure of human placental cells to mercury caused the accumulation of metal in the membranes and lowered the membrane fluidity (Boadi et al, 1992).…”

Section: Discussionsupporting

confidence: 87%

Mercury Content in Skin-Lightening Creams and Potential Hazards to the Health of Saudi Women

Al‐Saleh¹,

Al-Doush²

1997

Journal of Toxicology and Environmental Health

5

1

0

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It seems evident from a wealth of scientific research that mercury is toxic. Because of the nature of the Saudi markets, different brands of skin-lightening creams are widely available. In this study, 38 skin-lightening cream samples were collected and analyzed for mercury by inductively coupled plasma spectrometry after an acid digestion procedure. About 45% of the tested skin-lightening cream samples contained mercury at levels well above the FDA's acceptable limit of 1 ppm. These findings are alarming and have wide legal and educational implications for Saudi Arabia in particular and developing countries in general. Further investigation for possible adverse health effects is also needed.

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“…Similar results were found in the World Trade Center cohort in New York City [12]. Prenatal mercury exposure has also been associated with preterm birth [13], cleft palate, hydrocephalus, and heart defects [14–16]. …”

Section: Introductionsupporting

confidence: 74%

Mercury Levels in an Urban Pregnant Population in Durham County, North Carolina

Miranda

¹

,

Edwards

²

,

Maxson

³

2011

IJERPH

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The adverse effects of prenatal mercury exposure, most commonly resulting from maternal fish consumption, have been detected at very low exposure levels. The omega-3 fatty acids found in fish, however, have been shown to support fetal brain and vision development. Using data from a prospective, cohort study of pregnant women from an inland area in the US South, we sought to understand the fish consumption habits and associated mercury levels across subpopulations. Over 30% of women had at least 1 μg/L of mercury in their blood, and about 2% had blood mercury levels above the level of concern during pregnancy (≥3.5 μg/L). Mercury levels were higher among Asian/Pacific Islander, older, higher educated, and married women. Fish consumption from any source was reported by 2/3 of the women in our study, with older women more likely to consume fish. Despite eating more fish meals per week, lower income, lower educated women had lower blood mercury levels than higher income, higher educated women. This suggests the different demographic groups consume different types of fish. Encouraging increased fish consumption while minimizing mercury exposure requires careful crafting of a complex health message.

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“…This i s in agreement with other studies that indicated a high tendency toward permeability of the placenta to methylmercury (Pitkin et al, 1975;Suzuki et al, 1971;Koos & Longo, 1976 Kuhnert et al (1981) found the highest concentration of inorganic mercury was in the placenta, suggesting a barrier role, but a significant correlation (r = .62) was also found between the maternal and fetal plasma inorganic mercury levels. Animal data are also in agreement with human observations (Gale & Ferm, 1971;Gale & Hanlon, 1976;Gale, 1981;Holt & Webb, 1986). It has been recently reported that exposure of human placental cells to mercury caused the accumulation of metal in the membranes and lowered the Downloaded by [Chulalongkorn University] at 03:16 27 December 2014 membrane fluidity (Boadi et al, 1992).…”

Section: Discussionsupporting

confidence: 86%

Mercury Content in Skin-Lightening Creams and Potential Hazards to the Health of Saudi Women

Al‐Saleh

¹

,

Al-Doush

²

1997

Journal of Toxicology and Environmental Health

View full text Add to dashboard Cite

It seems evident from a wealth of scientific research that mercury is toxic. Because of the nature of the Saudi markets, different brands of skin-lightening creams are widely available. In this study, 38 skin-lightening cream samples were collected and analyzed for mercury by inductively coupled plasma spectrometry after an acid digestion procedure. About 45% of the tested skin-lightening cream samples contained mercury at levels well above the FDA's acceptable limit of 1 ppm. These findings are alarming and have wide legal and educational implications for Saudi Arabia in particular and developing countries in general. Further investigation for possible adverse health effects is also needed.

show abstract

Embryopathic effects of mercuric salts

Cited by 62 publications

References 12 publications

Mercury Content in Skin-Lightening Creams and Potential Hazards to the Health of Saudi Women

Mercury Content in Skin-Lightening Creams and Potential Hazards to the Health of Saudi Women

Mercury Levels in an Urban Pregnant Population in Durham County, North Carolina

Mercury Content in Skin-Lightening Creams and Potential Hazards to the Health of Saudi Women

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