Embryonal rhabdomyosarcoma of the uterine cervix in a pregnant woman

Meşeci, Elif; Öncüloğlu, Cem; İnce, Ümit; Teomete, M.; Eser, S; Demirkıran, Fuat

doi:10.1016/j.tjog.2013.10.042

Cited by 8 publications

(12 citation statements)

References 20 publications

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“…In another recently described case, a FIGO stage 1A embryonal RMS was diagnosed at 30 weeks of gestation. Interestingly, there was a delay in diagnosis in this case too as a polyp noted at 6 weeks was initially thought benign ( Meseci et al, 2014 ). In this case the decision was made to delay treatment until foetal lung maturity was achieved at 34 weeks.…”

Section: Discussionmentioning

confidence: 84%

“…Cancer affects approximately 1 in 1000 pregnancies and is expected to become increasingly common. The most frequently diagnosed cancers in pregnancy include breast cancer, cervical cancer, melanoma, lymphoma and leukaemia ( Meseci et al, 2014 ). Cervical cancer makes up approximately 25% of cancers diagnosed in pregnancy ( Meseci et al, 2014 ).…”

Section: Introductionmentioning

confidence: 99%

“…The most frequently diagnosed cancers in pregnancy include breast cancer, cervical cancer, melanoma, lymphoma and leukaemia ( Meseci et al, 2014 ). Cervical cancer makes up approximately 25% of cancers diagnosed in pregnancy ( Meseci et al, 2014 ). Nevertheless, the literature to inform evidence-based practice in this situation remains limited.…”

Section: Introductionmentioning

confidence: 99%

“…There are many factors which may be associated with this alarming trend including; delaying pregnancy into later reproductive years, the potential influence that pregnancy has on tumour growth, and the increased likelihood of diagnosis associated with increased interaction with health services ( Meseci et al, 2014 ).…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Wrong place at the wrong time: A case of cervical embryonal rhabdomyosarcoma in pregnancy

Taghavi

Sykes²,

Innes

et al. 2015

Gynecologic Oncology Reports

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Section: Discussionmentioning

confidence: 84%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Wrong place at the wrong time: A case of cervical embryonal rhabdomyosarcoma in pregnancy

Taghavi

Sykes²,

Innes

et al. 2015

Gynecologic Oncology Reports

View full text Add to dashboard Cite

show abstract

“…Immunohistochemical staining is now the optimal diagnostic method for RMS [ 11 ], which is typically positive for one or more muscle-specific markers, including desmin, muscle-specific actin, MyoD1, myoglobin, and/or myogenin [ 4 , 12 , 13 ]. In our patient, the tumor was positive for desmin, myogenin, and MyoD1.…”

Section: Discussionmentioning

confidence: 99%

Giant intrascrotal embryonal rhabdomyosarcoma in an adult: a case report and review of the literature

Gong

Gao

et al. 2018

J Med Case Reports

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BackgroundIntrascrotal embryonal rhabdomyosarcoma in adults is a rare tumor with high aggression and a poor prognosis. We report our patient’s case and review the relevant literature to improve the understanding of this rare disease.Case presentationA 21-year-old Han Chinese man presented to our hospital with a right intrascrotal mass of 1 year’s duration. His physical examination revealed an enlarged right scrotum containing a huge tender mass measuring about 10 × 7 cm. Ordinary and contrast-enhanced ultrasonography showed a solid mass in the right scrotum, which was suspected to be a malignant tumor. An abdominopelvic computed tomographic scan revealed metastases in the retroperitoneal lymph nodes. The patient was diagnosed with malignant testicular tumor and underwent a right radical orchiectomy by an inguinal approach. Postoperative pathological examination suggested an intrascrotal embryonal rhabdomyosarcoma.ConclusionsIntrascrotal embryonal rhabdomyosarcoma is a rare but highly aggressive tumor. Clinical and imaging manifestations of this tumor are nonspecific, so the definitive diagnosis depends on postoperative pathology and immunohistochemistry. Early suspicion, radical orchiectomy, accurate pathologic diagnosis, and adjuvant chemotherapy and/or radiotherapy are the keys to optimal prognosis.

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Embryonic cervical rhabdomyosarcoma complicated with uterine inversion with cerebral venous sinus thrombosis as the first symptom: a case report and literature review

Zhang

Han

et al. 2021

J Int Med Res

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The probability of rhabdomyosarcoma occurring in the cervix is less than 0.5% and may be associated with a pathogenic dicer 1, ribonuclease III ( DICER1) gene variation. Tumour-induced hypercoagulability and high levels of cancer antigen (CA) 125 are risk factors for cerebral venous sinus thrombosis (CVST). In addition, although nonpuerperal uterine inversion is very rare and is usually caused by leiomyomas from the uterus, large cervical masses can also be the cause. This case report describes a 24-year-old woman with uterine inversion caused by an embryonic cervical rhabdomyosarcoma that presented with CVST as her first symptom. The patient underwent laparoscopic total uterus and bilateral salpingectomy, during which the uterus was found to be completely inverted. Postoperative pathology confirmed embryonic cervical rhabdomyosarcoma. The patient quickly developed lung and para-aortic lymph node metastases. Two months later, the patient died of complications. When coagulation indices in patients with tumours are abnormal, especially when the levels of D-dimer and CA125 increase, it is recommended that anticoagulant therapy is administered in a timely manner to prevent the occurrence of CVST. Furthermore, for large cervical tumours, physicians should also be alert to the occurrence of uterine inversion.

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Embryonal rhabdomyosarcoma of the uterine cervix in a pregnant woman

Cited by 8 publications

References 20 publications

Wrong place at the wrong time: A case of cervical embryonal rhabdomyosarcoma in pregnancy

Wrong place at the wrong time: A case of cervical embryonal rhabdomyosarcoma in pregnancy

Giant intrascrotal embryonal rhabdomyosarcoma in an adult: a case report and review of the literature

Embryonic cervical rhabdomyosarcoma complicated with uterine inversion with cerebral venous sinus thrombosis as the first symptom: a case report and literature review

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