Embryonal Atresia of the Fourth Ventricle

Wj, Gardner; Lj, McCormack; Df, Dohn

doi:10.3171/jns.1960.17.2.0226

Cited by 54 publications

(2 citation statements)

References 13 publications

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“…The hypothesis of aberration during the embryonic life considers the following arguments: coincidence with other frequent central nervous system malformations and histological differences between normal and congenitally deformed structures [4,18,19,20,21,22,23]. …”

Section: Discussionmentioning

confidence: 99%

Cerebellopontine Angle Arachnoid Cyst Harbouring Ectopic Neuroglia

Ariai¹,

Koerbel²,

Bornemann

et al. 2005

Pediatr Neurosurg

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Arachnoid cysts are collections of cerebrospinal fluid covered by arachnoidal cells and collagen. They may have a congenital or acquired origin. We present the case of a 7-year-old boy with a cerebellopontine angle arachnoid cyst harbouring a portion of neuroglia. Microscopically, the cyst wall consisted of a delicate fibrovascular membrane lined by a layer of arachnoidal cells. A thin layer of glial tissue ran the whole length of the cyst wall. This finding supports a congenital origin for this case. Cerebellopontine angle arachnoid cysts harbouring neuroglia without ependymal elements are very rare lesions and may be successfully treated by surgical resection.

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Section: Discussionmentioning

confidence: 99%

Cerebellopontine Angle Arachnoid Cyst Harbouring Ectopic Neuroglia

Ariai¹,

Koerbel²,

Bornemann

et al. 2005

Pediatr Neurosurg

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“…Other publications even showed tumour-induced neurovascular uncoupling causing contralateral pseudo-dominance at fMRI in few cases [8]. In order to validate the conspicuous fMRI findings, which revealed the transhemispheric configuration (dominant Wernicke area: left, Broca centre: strongly lateralized to the right hemisphere), the Wada test [9] was carried out. A 5F guide catheter (5F Envoy, Codman, Raynham, MA, USA) was advanced into the cervical part of the left internal carotid artery (ICA).…”

Section: Case Reportmentioning

confidence: 99%

Dissociated Crossed Speech Areas in a Tumour Patient

et al. 2017

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In the past, the eloquent areas could be deliberately localised by the invasive Wada test. The very rare cases of dissociated crossed speech areas were accidentally found based on the clinical symptomatology. Today functional magnetic resonance imaging (fMRI)-based imaging can be employed to non-invasively localise the eloquent areas in brain tumour patients for therapy planning. A 41-year-old, left-handed man with a low-grade glioma in the left frontal operculum extending to the insular cortex, tension headaches, and anomic aphasia over 5 months underwent a pre-operative speech area localisation fMRI measurement, which revealed the evidence of the transhemispheric disposition, where the dominant Wernicke speech area is located on the left and the Broca’s area is strongly lateralised to the right hemisphere. The outcome of the Wada test and the intraoperative cortico-subcortical stimulation mapping were congruent with this finding. After tumour removal, language area function was fully preserved. Upon the occurrence of brain tumours with a risk of impaired speech function, the rare dissociate crossed speech areas disposition may gain a clinically relevant meaning by allowing for more extended tumour removal. Hence, for its identification, diagnostics which take into account both brain hemispheres, such as fMRI, are recommended.

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