Embolization Tools

Golzarian, Jafar; Siskin, Gary P.; Sharafuddin, Mel J.; Mimura, Hidefumi; Coldwell, Douglas M.

doi:10.1007/3-540-33256-1_2

Cited by 6 publications

(4 citation statements)

References 110 publications

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“…Transarterial embolization is the intentional occlusion of a blood vessel by introduction of an agent via a catheter placed within the vasculature that creates a blockade to further blood flow. Embolization agents come in many forms and can include devices such as balloons and coils, liquids such as glue, gelling polymer solutions and sclerosing agents such as alcohol, or most commonly particles or microspherical embolics made from hydrogels [1][2][3]. Many of the commercially available embolic materials are colored with dyes in order to make them easier to see during handling and administration but they are difficult to detect during and after administration because they are not directly visible under standard x-ray, magnetic resonance (MR), ultrasound or nuclear medicine imaging techniques.…”

mentioning

confidence: 99%

Bench-To-Clinic Development of Imageable Drug-Eluting Embolization Beads: Finding the Balance

et al. 2018

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This review describes the historical development of an imageable spherical embolic agent and focuses on work performed in collaboration between Biocompatibles UK Ltd (a BTG International group company) and the NIH to demonstrate radiopaque bead utility and bring a commercial offering to market that meets a clinical need. Various chemistries have been investigated and multiple prototypes evaluated in search of an optimized product with the right balance of handling and imaging properties. Herein, we describe the steps taken in the development of DC Bead LUMI™, the first commercially available radiopaque drug-eluting bead, ultimately leading to the first human experience of this novel embolic agent in the treatment of liver tumors.

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mentioning

confidence: 99%

Bench-To-Clinic Development of Imageable Drug-Eluting Embolization Beads: Finding the Balance

et al. 2018

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“…IR encompasses a broad spectrum of interventional procedures, including embolization. Embolization with liquid agents has become a widely used treatment for arteriovenous malformations, varicoceles, gastrointestinal bleedings, aneurysms, and pseudoaneurysms (Golzarian et al 2006 ). These procedures require advanced haptic skills, knowledge of subsequent steps, and a proper risk assessment.…”

Section: Introductionmentioning

confidence: 99%

Three-dimensional simulator: training for beginners in endovascular embolization with liquid agents

et al. 2021

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Background To design a simulator for novices without prior experience in embolization with liquid agents such as n-Butyl cyanoacrylate (n-BCA) and to evaluate the simulator using surveys and post hoc video analysis. Materials and methods The simulator was created using computer-aided design software and three-dimensionally printed. Before an embolization, trainees completed questionnaires regarding their level of expertise and self-reported confidence level. The participants were shown an instruction video and each participant performed four embolizations on the simulator. Subsequently, the participants completed surveys on self-reported confidence level and assessed the simulator’s face and content validity. Results Five experts and twelve novices trained on the simulator. The experts were radiology residents and fellows with at least 5 years of work experience in interventional radiology. The novices were medical students and radiology residents without any previous experience with embolization. Based on the surveys, the experts assessed the simulator as very useful for embolization training. Performance, e.g. mean duration embolization between experts (mean ± standard deviation = 189 ± 42 s) and novices (mean ± standard deviation = 235 ± 66 s) were significantly different (p = .001). The overall simulation of the embolization process, simulated complications, and educational capabilities of the simulator were evaluated positively. In the novice group the self-reported confidence level significantly increased (p = .001). Conclusion The liquid embolization simulator proposed here is a suitable educational tool for training embolization procedures. It reduces the duration of embolization procedures and improves the confidence level of beginners in embolization.

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“…Coils are extensively used to treat intra-cranial aneurysms and in the peripheral system to achieve a definitive occlusion (1)(2)(3)(4). With coils a mechanical occlusion of the embolized vessel is achieved.…”

Section: Introductionmentioning

confidence: 99%

“…With coils a mechanical occlusion of the embolized vessel is achieved. The degree of luminal packing is the most important parameter for obtaining cross-sectional occlusion and reducing the risk of recanalization (2,3,4). For peripheral embolization, fibered coils with Dacron or Nylon fiber bundles tied to the primary platinum coil enhance the thrombogenicity of the coil (3).…”

Section: Introductionmentioning

confidence: 99%

Midterm Recanalization after Arterial Embolization Using Hydrogel-Coated Coils versus Fibered Coils in an Animal Model

Fohlen

Namur²,

Ghegediban³

et al. 2019

Journal of Vascular and Interventional Radiology

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Embolization Tools

Cited by 6 publications

References 110 publications

Bench-To-Clinic Development of Imageable Drug-Eluting Embolization Beads: Finding the Balance

Bench-To-Clinic Development of Imageable Drug-Eluting Embolization Beads: Finding the Balance

Three-dimensional simulator: training for beginners in endovascular embolization with liquid agents

Midterm Recanalization after Arterial Embolization Using Hydrogel-Coated Coils versus Fibered Coils in an Animal Model

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