Embolization of vascular malformations

Influence of Sonication on Morphological Properties of Poly(Vinyl Acetate) Particles Produced Through Suspension Polymerization

“…Besides, the density of VE agents must be properly controlled, since dense materials can occlude the catheter during the application due to sedimentation and light materials can lead to bad occlusion of the vessel . It is important to say that PVAc particles produced through suspension polymerization are excellent materials for vascular embolization procedures as a result of its good swelling capacity while in contact with blood flow, capacity to produce poly(vinyl alcohol) through caustic hydrolysis, low glass transition temperature and low manageable densities …”

“…[3] It is important to say that PVAc particles produced through suspension polymerization are excellent materials for vascular embolization procedures as a result of its good swelling capacity while in contact with blood flow, capacity to produce poly(vinyl alcohol) through caustic hydrolysis, low glass transition temperature and low manageable densities. [3][4][5][6][7][8][9] During the suspension polymerization of vinyl acetate (VAc), the agitation speed may reduce the final density of the particles. [9] This can occur when small water droplets are encapsulated in the organic phase, which can be eliminated during the drying step, leading to formation of a porous structure in the polymer matrix.…”