2000
DOI: 10.1177/15910199000060s129
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Embolization of Arteriovenous Malformation with Diluted Mixture of NBCA

Abstract: The technique of nidus embolization with N-butyl-2-cyanoacrylate (NBCA) glue is presented. The microcatheter is navigated into the nidus and the tip is set in a wedged position. A diluted mixture of NBCA in ethiodized oil (a 25% mixture is mainly used) is injected very slowly, using complete column technique. Using this technique, the progression of glues in the nidus can be seen easily, which leads to improve accuracy and effectiveness of embolization. The mean blood pressure is maintained 15% to 20%… Show more

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Cited by 21 publications
(13 citation statements)
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“…In Situ Polymerization -nBCA N-butyl-2-cyanoacrylate (nBCA) (e.g., TruFill), commonly known as "glue," is a clear, free-flowing liquid that has used for embolization since the mid-1980s. [292] It is also widely used in wound healing since it provides an antimicrobial barrier with 99% efficacy for at least 72 h. [11b] nBCA has relatively low viscosity of about 10 mPa s. [293] It adheres to tissue by in situ polymerization upon contact with tissue fluid, an ionic and high-pH environment, creating a glue effect. The polymerization process is anionic (induced by OH − ) and exothermic (released heat is up to 80 °C and can be very painful).…”
Section: Droplet Agentsmentioning
confidence: 99%
“…In Situ Polymerization -nBCA N-butyl-2-cyanoacrylate (nBCA) (e.g., TruFill), commonly known as "glue," is a clear, free-flowing liquid that has used for embolization since the mid-1980s. [292] It is also widely used in wound healing since it provides an antimicrobial barrier with 99% efficacy for at least 72 h. [11b] nBCA has relatively low viscosity of about 10 mPa s. [293] It adheres to tissue by in situ polymerization upon contact with tissue fluid, an ionic and high-pH environment, creating a glue effect. The polymerization process is anionic (induced by OH − ) and exothermic (released heat is up to 80 °C and can be very painful).…”
Section: Droplet Agentsmentioning
confidence: 99%
“…Alternative theories include capillary instability and weakness as a consequence of neovascularisation 41 and occlusive hyperaemia due to obstruction of adjacent venous outflow and stagnant arterial flow in previous AVM feeding vessels 42 . It is recommended that the blood pressure is maintained at 15-20% below the patient's baseline blood pressure but this is not evidencebased 43,44 . Diligent avoidance of hypertension and maintenance of normotension or controlled hypotension are the aims of the perioperative care of these patients.…”
Section: Anaesthetic Considerationsmentioning
confidence: 99%
“…These types of microcatheters are not compatible with DMSO. Despite the low obliteration rates observed with NBCA [20], we selected this embolic agent because of the penetration rate based on the dilution with lipiodol, the distal placement of the microcatheter, the compact nidus of the AVM, and the absence of a fistulous pattern. We used the same material for the ipsilateral AICA catheterization and embolization.…”
Section: Discussionmentioning
confidence: 99%