Embolization for Treatment of Gastrointestinal Hemorrhage Secondary to Recurrent Renal Cell Carcinoma

Abstract

Massive gastrointestinal hemorrhage secondary to metastatic renal cell carcinoma involving the jejunum is rare but has been previously described in the medical literature. Treatment options for metastatic renal cell carcinoma are limited, but transcatheter arterial embolization can be performed to control gastrointestinal hemorrhage either alone or prior to surgical resection. We describe a case of successful transcatheter arterial embolization for control of massive gastrointestinal hemorrhage secondary to locally recurrent renal cell carcinoma invading the jejunum and review the literature. Arteriography provided both the diagnosis of recurrent disease and the means of therapy.

Local recurrence of renal cell carcinoma presented with massive gastrointestinal bleeding: management with renal artery embolization

“…Duodenum is the most common site of GI involvement, given its close proximity to the right kidney (Ouellet et al, 2018). Clinical symptoms of GI involvement are usually related to the tumor-related hemorrhage including melena (Ohmura et al, 2000;Ali et al, 2013), hematemesis (Blake et al, 1995), hematochezia (Ali et al, 2013), haemobilia (Lynch-Nyhan et al, 1987) and iron-deficiency anemia (Kobak et al, 2006), or bowel obstruction (Sadler et al, 2007). Sixty-nine percent of patients with solitary GI metastasis from RCC present with GIB, but massive GIB is a rare occurrence (Ohmura et al, 2000).…”